Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 2/20 | 0.46 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.46 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.46 |
| ▸ | TACR2 | P21452 | 2/20 | 0.46 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.46 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.46 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | SHBG | P04278 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.46 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.46 |
| ▸ | HTR2C | P28335 | 1/20 | 0.46 |
| ▸ | HSPE1 | P61604 | 1/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.46 |
| ▸ | TST | Q16762 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16890696 | 0.94 | CA1 (0.40) | — | |
| SCHEMBL29508336 | 0.82 | ESR1 (0.51) | ESR1ADRA2AADORA3TACR2SLC6A2 | |
| SCHEMBL27871822 | 0.81 | LPAR1 (0.48) | ESR1ADRA2AADORA3TACR2SLC6A2 | |
| SCHEMBL941555 | 0.81 | ESR1 (0.61) | ESR1ADRA2AADORA3TACR2SLC6A2 | |
| SCHEMBL9505414 | 0.81 | ESR1 (0.61) | ESR1ADRA2AADORA3TACR2SLC6A2 | |
| SCHEMBL8052300 | 0.81 | ESR1 (0.61) | ESR1ADRA2AADORA3TACR2SLC6A2 | |
| SCHEMBL8444312 | 0.81 | ESR1 (0.61) | ESR1ADRA2AADORA3TACR2SLC6A2 | |
| SCHEMBL173284 | 0.81 | ESR1 (0.61) | ESR1ADRA2AADORA3TACR2SLC6A2 | |
| SCHEMBL5510956 | 0.81 | ESR1 (0.61) | ESR1ADRA2AADORA3TACR2SLC6A2 | |
| SCHEMBL93802 | 0.81 | ESR1 (0.61) | ESR1ADRA2AADORA3TACR2SLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11856806-B2 | Disubstituted dl aryloxybenzoh eterodi azole compounds | ENI S.P.A. (IT) | 2023-12-26 | — | — | US | disclosed |
| EP-3867333-B1 | DISUBSTITUTED DIARYLOXYBENZOHETERODIAZOLE COMPOUNDS | ENI SPA (IT) | 2022-09-14 | — | — | EP | disclosed |
| US-20210367176-A1 | DISUBSTITUTED DL ARYLOXYBENZOH ETERODI AZOLE COMPOUNDS | ENI S.P.A. (US) | 2021-11-25 | — | — | US | disclosed |
| CN-113166138-A | Disubstituted diaryloxybenzoheterodiazole compounds | 艾尼股份公司 | 2021-07-23 | — | — | CN | disclosed |
| WO-2020079654-A1 | DISUBSTITUTED DL ARYLOXYBENZOH ETERODI AZOLE COMPOUNDS | ENI S.P.A. (IT) | 2020-04-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210367176-A1 | DISUBSTITUTED DL ARYLOXYBENZOH ETERODI AZOLE COMPOUNDS | CCND3, CCND2, CCND1 | ESR1 132/4885ADRA2A 3802/4885ADORA3 2804/4885 |
| US-11856806-B2 | Disubstituted dl aryloxybenzoh eterodi azole compounds | LSS, CCND1, CCND2 | ESR1 219/4885ADRA2A 4640/4885ADORA3 4302/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.