Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM1 | P11229 | 14/20 | 0.59 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.40 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.38 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30436296 | 0.90 | CHRM1 (0.57) | CHRM1NPC1RAB9A | |
| SCHEMBL21858982 | 0.87 | CHRM1 (0.51) | CHRM1 | |
| SCHEMBL21859083 | 0.85 | CHRM1 (0.66) | CHRM1APOBEC3ANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL21858992 | 0.85 | CHRM1 (0.53) | CHRM1SMN1; SMN2 | |
| SCHEMBL21859075 | 0.81 | CHRM1 (0.57) | CHRM1NPC1RAB9A | |
| SCHEMBL21859015 | 0.81 | CHRM1 (0.67) | CHRM1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL30435828 | 0.81 | CHRM1 (0.57) | CHRM1NPC1RAB9A | |
| SCHEMBL21859041 | 0.80 | CHRM1 (0.66) | CHRM1SMN1; SMN2 | |
| SCHEMBL21858933 | 0.80 | CHRM1 (0.55) | CHRM1NPC1RAB9A | |
| SCHEMBL22322560 | 0.80 | CHRM1 (0.55) | CHRM1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020079606-A1 | PYRROLO-PYRIDAZINE DERIVATIVES AS MUSCARINIC M1 RECEPTOR POSITIVE ALLOSTERIC MODULATORS | SUVEN LIFE SCIENCES LIMITED (IN) | 2020-04-23 | — | — | WO | disclosed |