Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 8/20 | 0.70 |
| ▸ | MEN1 | O00255 | 7/20 | 0.70 |
| ▸ | POLB | P06746 | 7/20 | 0.70 |
| ▸ | GAA | P10253 | 6/20 | 0.70 |
| ▸ | GFER | P55789 | 2/20 | 0.70 |
| ▸ | GALK1 | P51570 | 1/20 | 0.70 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.70 |
| ▸ | DYRK1A | Q13627 | 8/20 | 0.61 |
| ▸ | ATM | Q13315 | 1/20 | 0.61 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.61 |
| ▸ | MAPT | P10636 | 7/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.56 |
| ▸ | PLIN1 | O60240 | 2/20 | 0.56 |
| ▸ | PLIN5 | Q00G26 | 2/20 | 0.56 |
| ▸ | ABHD5 | Q8WTS1 | 2/20 | 0.56 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.56 |
| ▸ | ERO1A | Q96HE7 | 1/20 | 0.54 |
| ▸ | HPGD | P15428 | 2/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2185917 | 1.00 | KMT2A (0.70) | KMT2AMEN1POLBGAAGFER | |
| SCHEMBL14444416 | 0.90 | KMT2A (0.62) | KMT2AMEN1POLBGAAGFER | |
| SCHEMBL2184453 | 0.79 | DYRK1A (0.84) | KMT2AMEN1POLBGAAGFER | |
| SCHEMBL2184451 | 0.79 | DYRK1A (0.84) | KMT2AMEN1POLBGAAGFER | |
| SCHEMBL28302105 | 0.76 | DYRK1A (1.00) | KMT2AMEN1POLBGAAGFER | |
| SCHEMBL18420224 | 0.74 | DYRK1A (1.00) | KMT2AMEN1POLBGAAGFER | |
| SCHEMBL18844753 | 0.74 | DYRK1A (1.00) | KMT2AMEN1POLBGAAGFER | |
| SCHEMBL18420223 | 0.74 | DYRK1A (1.00) | KMT2AMEN1POLBGAAGFER | |
| SCHEMBL3760714 | 0.70 | DYRK1A (1.00) | KMT2AMEN1POLBGAAGFER | |
| SCHEMBL3760719 | 0.70 | DYRK1A (1.00) | KMT2AMEN1POLBGAAGFER |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9949980-B2 | Drugs to prevent HPV infection | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2018-04-24 | — | — | US | disclosed |
| US-20150297602-A1 | DRUGS TO PREVENT HPV INFECTION | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2015-10-22 | — | — | US | disclosed |
| US-9066951-B2 | Drugs to treat HPV infection | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2015-06-30 | — | — | US | disclosed |
| US-20110165220-A1 | DRUGS TO PREVENT HPV INFECTION | WISCONSIN ALUMNI RESEARCH FOUNDATION | 2011-07-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110165220-A1 | DRUGS TO PREVENT HPV INFECTION | VHL, PHF13, CDKN1A | KMT2A 400/4885MEN1 1211/4885POLB 2460/4885 |
| US-20150297602-A1 | DRUGS TO PREVENT HPV INFECTION | VHL, PHF13, CDKN1A | KMT2A 400/4885MEN1 1211/4885POLB 2460/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.