Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 16/20 | 0.63 |
| ▸ | CNR2 | P34972 | 13/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2186134 | 0.88 | CNR2 (0.61) | CNR1CNR2 | |
| SCHEMBL2186950 | 0.87 | CNR1 (0.65) | CNR1CNR2 | |
| SCHEMBL3082527 | 0.81 | CNR2 (0.42) | CNR1CNR2 | |
| SCHEMBL5114719 | 0.75 | CNR2 (0.72) | CNR1CNR2 | |
| SCHEMBL496518 | 0.75 | CNR2 (0.72) | CNR1CNR2 | |
| SCHEMBL2715501 | 0.75 | CNR1 (0.67) | CNR1CNR2 | |
| SCHEMBL495960 | 0.74 | CNR2 (0.74) | CNR1CNR2 | |
| SCHEMBL496561 | 0.74 | CNR2 (0.74) | CNR1CNR2 | |
| SCHEMBL495971 | 0.74 | CNR2 (0.74) | CNR1CNR2 | |
| SCHEMBL2185805 | 0.74 | CNR1 (0.63) | CNR1CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8030345-B2 | Tricyclic pyrazole derivatives as cannabinoid receptor modulators | CADILA HEALTHCARE LIMITED (IN) | 2011-10-04 | — | — | US | claimed |
| EP-2343302-A1 | TRICYCLIC PYRAZOLE DERIVATIVES AS CANNABINOID RECEPTOR MODULATORS | CADILA HEALTHCARE LIMITED (IN) | 2011-07-13 | — | — | EP | claimed |
| US-8030345-B2 | Tricyclic pyrazole derivatives as cannabinoid receptor modulators | CADILA HEALTHCARE LIMITED (IN) | 2011-10-04 | — | — | US | disclosed |
| EP-2343302-A1 | TRICYCLIC PYRAZOLE DERIVATIVES AS CANNABINOID RECEPTOR MODULATORS | CADILA HEALTHCARE LIMITED (IN) | 2011-07-13 | — | — | EP | disclosed |