Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY5R | Q15761 | 4/20 | 0.36 |
| ▸ | NPY4R | P50391 | 4/20 | 0.36 |
| ▸ | NPY1R | P25929 | 3/20 | 0.36 |
| ▸ | C3AR1 | Q16581 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | NPY2R | P49146 | 1/20 | 0.33 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.33 |
| ▸ | NPFFR1 | Q9GZQ6 | 1/20 | 0.32 |
| ▸ | AKT1 | P31749 | 1/20 | 0.32 |
| ▸ | FNTA | P49354 | 1/20 | 0.31 |
| ▸ | FNTB | P49356 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KLK7 | P49862 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | HRH1 | P35367 | 2/20 | 0.31 |
| ▸ | KISS1R | Q969F8 | 1/20 | 0.30 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.30 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.30 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.30 |
| ▸ | NMT2 | O60551 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17722924 | 0.91 | NPY5R (0.39) | NPY5RNPY4RNPY1RC3AR1POLB | |
| SCHEMBL21034050 | 0.91 | C3AR1 (0.38) | NPY5RNPY4RNPY1RC3AR1POLB | |
| SCHEMBL18909037 | 0.90 | NPY5R (0.36) | NPY5RNPY4RNPY1RC3AR1POLB | |
| SCHEMBL20889020 | 0.89 | NPY5R (0.36) | NPY5RNPY4RNPY1RC3AR1POLB | |
| SCHEMBL21034051 | 0.88 | NPY5R (0.35) | NPY5RNPY4RNPY1RC3AR1POLB | |
| SCHEMBL20935177 | 0.88 | NPY5R (0.35) | NPY5RNPY4RNPY1RC3AR1POLB | |
| SCHEMBL19681473 | 0.84 | NPY5R (0.42) | NPY5RNPY4RNPY1RNPY2RNMT2 | |
| SCHEMBL18909079 | 0.82 | NPY5R (0.39) | NPY5RNPY4RNPY1RC3AR1POLB | |
| SCHEMBL17722903 | 0.82 | NPY5R (0.40) | NPY5RNPY4RNPY1RC3AR1POLB | |
| SCHEMBL18937746 | 0.82 | NPY5R (0.40) | NPY5RNPY4RNPY1RC3AR1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020236792-A1 | CD19 BINDING MOLECULES AND USES THEREOF | NOVARTIS AG (CH) | 2020-11-26 | — | — | WO | disclosed |
| WO-2020052692-A2 | BINDING MOLECULES AGAINST CD3 AND USES THEREOF | NOVARTIS AG (CH) | 2020-03-19 | — | — | WO | disclosed |