Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90B1 | P14625 | 5/20 | 0.73 |
| ▸ | HSP90AA1 | P07900 | 13/20 | 0.67 |
| ▸ | HSP90AB1 | P08238 | 13/20 | 0.67 |
| ▸ | ERBB2 | P04626 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21861886 | 0.88 | HSP90AA1 (0.67) | HSP90B1HSP90AA1HSP90AB1ERBB2 | |
| SCHEMBL16487229 | 0.84 | HSP90B1 (1.00) | HSP90B1HSP90AA1HSP90AB1 | |
| SCHEMBL17900416 | 0.80 | HSP90AA1 (0.67) | HSP90B1HSP90AA1HSP90AB1ERBB2 | |
| SCHEMBL27286422 | 0.80 | HSP90AA1 (1.00) | HSP90B1HSP90AA1HSP90AB1ERBB2 | |
| SCHEMBL16486667 | 0.76 | HSP90B1 (1.00) | HSP90B1HSP90AA1HSP90AB1ERBB2 | |
| SCHEMBL17897956 | 0.75 | HSP90AA1 (0.60) | HSP90B1HSP90AA1HSP90AB1ERBB2 | |
| SCHEMBL3113898 | 0.73 | HSP90AA1 (0.72) | HSP90B1HSP90AA1HSP90AB1ERBB2 | |
| SCHEMBL3125722 | 0.72 | HSP90AA1 (0.70) | HSP90B1HSP90AA1HSP90AB1ERBB2 | |
| SCHEMBL3114409 | 0.72 | HSP90AA1 (0.76) | HSP90B1HSP90AA1HSP90AB1ERBB2 | |
| SCHEMBL17900222 | 0.71 | HSP90AA1 (0.68) | HSP90AA1HSP90AB1ERBB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200102312-A1 | SELECTIVE GRP94 INHIBITORS AND USES THEREOF | MEMORIAL SLOAN-KETTERING CANCER CENTER | 2020-04-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200102312-A1 | SELECTIVE GRP94 INHIBITORS AND USES THEREOF | HSP90B1, HSP90AB2P, HSPE1 | HSP90B1 1/4885HSP90AA1 9/4885HSP90AB1 4/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.