Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 20/20 | 0.82 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17502320 | 0.90 | KCNH2 (1.00) | KCNH2 | |
| SCHEMBL17502242 | 0.90 | KCNH2 (1.00) | KCNH2 | |
| SCHEMBL17502251 | 0.90 | KCNH2 (1.00) | KCNH2 | |
| SCHEMBL17502317 | 0.84 | KCNH2 (1.00) | KCNH2 | |
| SCHEMBL17502236 | 0.82 | KCNH2 (1.00) | KCNH2 | |
| SCHEMBL17502334 | 0.81 | KCNH2 (1.00) | KCNH2 | |
| SCHEMBL17502232 | 0.81 | KCNH2 (1.00) | KCNH2 | |
| SCHEMBL17502252 | 0.80 | KCNH2 (1.00) | KCNH2 | |
| SCHEMBL17502256 | 0.80 | KCNH2 (1.00) | KCNH2 | |
| SCHEMBL17502321 | 0.79 | KCNH2 (1.00) | KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3180329-B1 | TRIAZOLES AS NR2B RECEPTOR INHIBITORS | JANSSEN PHARMACEUTICALS INC (US) | 2020-03-18 | — | — | EP | disclosed |