⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22911115 | 0.77 | — | — | |
| SCHEMBL16121142 | 0.74 | MAPT (0.38) | — | |
| SCHEMBL21397739 | 0.71 | POLB (0.33) | — | |
| SCHEMBL324662 | 0.69 | — | — | |
| SCHEMBL21030220 | 0.66 | MAPT (0.35) | — | |
| SCHEMBL22083911 | 0.64 | — | — | |
| SCHEMBL24131510 | 0.64 | — | — | |
| SCHEMBL17624316 | 0.64 | — | — | |
| SCHEMBL21285317 | 0.64 | — | — | |
| SCHEMBL2067300 | 0.64 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020065614-A1 | MONOACYLGLYCEROL LIPASE MODULATORS | JANSSEN PHARMACEUTICA NV (BE) | 2020-04-02 | — | — | WO | disclosed |