Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.53 |
| ▸ | CYP1A1 | P04798 | 9/20 | 0.52 |
| ▸ | CYP1B1 | Q16678 | 9/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 8/20 | 0.52 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.52 |
| ▸ | ABCC1 | P33527 | 2/20 | 0.52 |
| ▸ | ABCG2 | Q9UNQ0 | 2/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | TP53 | P04637 | 3/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | HPGD | P15428 | 3/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.48 |
| ▸ | TNKS | O95271 | 2/20 | 0.48 |
| ▸ | MAOB | P27338 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | GLA | P06280 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21801178 | 0.89 | CYP1A1 (0.67) | CYP1A1CYP1B1CYP1A2ABCB1ABCC1 | |
| SCHEMBL25510572 | 0.87 | TNKS (0.60) | CYP1A1CYP1B1CYP1A2ABCB1ABCC1 | |
| SCHEMBL21801271 | 0.86 | ABCB1 (0.52) | CYSLTR1CYP1A1CYP1B1CYP1A2ABCB1 | |
| SCHEMBL30744107 | 0.86 | ABCB1 (0.52) | CYSLTR1CYP1A1CYP1B1CYP1A2ABCB1 | |
| SCHEMBL21801153 | 0.84 | ABCB1 (0.53) | CYSLTR1CYP1A1CYP1B1CYP1A2ABCB1 | |
| SCHEMBL21801095 | 0.84 | TDP1 (0.64) | CYP1A1CYP1B1CYP1A2KDM4EALDH1A1 | |
| SCHEMBL21801308 | 0.83 | ABCB1 (0.52) | CYSLTR1CYP1A1CYP1B1CYP1A2ABCB1 | |
| SCHEMBL28538523 | 0.81 | CYSLTR1 (0.56) | CYSLTR1CYP1A1CYP1B1CYP1A2ABCB1 | |
| SCHEMBL21886428 | 0.81 | MAOB (0.51) | CYSLTR1CYP1A1CYP1B1CYP1A2ABCB1 | |
| SCHEMBL21801128 | 0.81 | CYSLTR1 (0.44) | CYSLTR1CYP1A1CYP1B1CYP1A2ABCB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020053249-A1 | FLAVONE COMPOUNDS FOR THE TREATMENT AND PROPHYLAXIS OF HEPATITIS B VIRUS DISEASE | F. HOFFMANN-LA ROCHE AG (CH) | 2020-03-19 | — | — | WO | disclosed |