Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.38 |
| ▸ | CA1 | P00915 | 3/20 | 0.35 |
| ▸ | CA12 | O43570 | 2/20 | 0.35 |
| ▸ | CA7 | P43166 | 2/20 | 0.35 |
| ▸ | ACKR3 | P25106 | 2/20 | 0.33 |
| ▸ | NAMPT | P43490 | 1/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.32 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.32 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.32 |
| ▸ | CA2 | P00918 | 2/20 | 0.32 |
| ▸ | CTSK | P43235 | 1/20 | 0.32 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.30 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28362744 | 0.84 | CHRM2 (0.35) | CA14CA1CA12CA7HDAC1 | |
| SCHEMBL18400312 | 0.83 | CA14 (0.36) | CA14CA1CA12CA7HDAC1 | |
| SCHEMBL3469119 | 0.82 | CA14 (0.46) | CA14CA1CA12CA7NAMPT | |
| SCHEMBL16125928 | 0.81 | CA14 (0.39) | CA14CA1CA12CA7NAMPT | |
| SCHEMBL7737226 | 0.80 | CA14 (0.36) | CA14CA1CA12CA7NAMPT | |
| SCHEMBL10267170 | 0.80 | CA12 (0.43) | CA14CA1CA12CA7NAMPT | |
| SCHEMBL255184 | 0.79 | CA14 (0.38) | CA14CA1CA12CA7NAMPT | |
| SCHEMBL1962792 | 0.79 | MEN1 (0.45) | CA14CA1CA12CA7HDAC1 | |
| SCHEMBL18619385 | 0.79 | CA14 (0.40) | CA14CA1CA12CA7HDAC1 | |
| SCHEMBL4164699 | 0.78 | CA14 (0.41) | CA14CA1CA12CA7NAMPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020052509-A1 | SULFONAMIDE COMPOUND SERVING AS SODIUM CHANNEL BLOCKER AND USES THEREOF | 成都康弘药业集团股份有限公司 | 2020-03-19 | — | — | WO | disclosed |