SCHEMBL2186804

SCHEMBL2186804

CC1(C)CCc2c[nH]nc21

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21208806 0.64
SCHEMBL19979226 0.62
SCHEMBL16018997 0.61 OPRL1 (0.34)
SCHEMBL21208798 0.60
SCHEMBL21805985 0.60
SCHEMBL9538304 0.60
SCHEMBL14262994 0.59
SCHEMBL12507439 0.58 SMN1; SMN2 (0.31)
SCHEMBL11791980 0.58
SCHEMBL19542109 0.57

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1710234-B1 MALONONITRILE COMPOUND AND USE THEREOF SUMITOMO CHEMICAL CO (JP) 2011-07-13 EP disclosed
EP-1710234-B1 MALONONITRILE COMPOUND AND USE THEREOF SUMITOMO CHEMICAL CO (JP) 2011-07-13 EP disclosed
US-7541374-B2 Malononitrile compounds and use thereof SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2009-06-02 US disclosed
US-7541374-B2 Malononitrile compounds and use thereof SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2009-06-02 US disclosed
US-20070117854-A1 Malononitrile compounds and use thereof SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2007-05-24 US disclosed
US-20070117854-A1 Malononitrile compounds and use thereof SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2007-05-24 US disclosed
US-20070117854-A1 Malononitrile compounds and use thereof SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2007-05-24 US disclosed
US-7138361-B2 Herbicidal heterocycles E. I. DU PONT DE NEMOURS AND COMPANY (US) 2006-11-21 US disclosed
US-20060229205-A1 Herbicidal heterocycles COTTERMAN CLIFFORD D 2006-10-12 US disclosed
EP-1710234-A1 MALONONITRILE COMPOUND AND USE THEREOF Sumitomo Chemical Company, Limited (JP) 2006-10-11 EP disclosed
US-20040106520-A1 Herbicidal heterocycles E. I. DU PONT DE NEMOURS AND COMPANY 2004-06-03 US disclosed
EP-1337531-A2 HERBICIDAL HETEROCYCLES E. I. du Pont de Nemours and Company (US) 2003-08-27 EP disclosed
WO-2002044173-A2 HERBICIDAL HETEROCYCLES E. I. DU PONT DE NEMOURS AND COMPANY (US) 2002-06-06 WO disclosed