Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC9A3 | P48764 | 19/20 | 0.75 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.75 |
| ▸ | SLC9A5 | Q14940 | 2/20 | 0.75 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2189770 | 1.00 | SLC9A3 (0.75) | SLC9A3CYP2C9SLC9A5CYP2D6 | |
| SCHEMBL2188847 | 0.92 | SLC9A3 (0.78) | SLC9A3CYP2C9SLC9A5CYP2D6 | |
| SCHEMBL2188843 | 0.92 | SLC9A3 (0.78) | SLC9A3CYP2C9SLC9A5CYP2D6 | |
| SCHEMBL2186482 | 0.92 | SLC9A3 (0.78) | SLC9A3CYP2C9SLC9A5CYP2D6 | |
| SCHEMBL2189080 | 0.90 | SLC9A3 (0.75) | SLC9A3CYP2C9SLC9A5CYP2D6 | |
| SCHEMBL2189085 | 0.90 | SLC9A3 (0.75) | SLC9A3CYP2C9SLC9A5CYP2D6 | |
| SCHEMBL2261139 | 0.88 | SLC9A3 (0.72) | SLC9A3CYP2C9SLC9A5CYP2D6 | |
| SCHEMBL2264919 | 0.88 | SLC9A3 (0.77) | SLC9A3CYP2C9SLC9A5CYP2D6 | |
| SCHEMBL2188477 | 0.88 | SLC9A3 (0.77) | SLC9A3CYP2C9SLC9A5CYP2D6 | |
| SCHEMBL2261133 | 0.88 | SLC9A3 (0.72) | SLC9A3CYP2C9SLC9A5CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2342178-A1 | SUBSTITUTED AMINOINDANES AND ANALOGS THEREOF, AND THE PHARMACEUTICAL USE THEREOF | Sanofi-Aventis (FR) | 2011-07-13 | — | — | EP | claimed |
| WO-2010025856-A1 | SUBSTITUTED AMINOINDANES AND ANALOGS THEREOF, AND THE PHARMACEUTICAL USE THEREOF | SANOFI-AVENTIS (FR) | 2010-03-11 | — | — | WO | claimed |