Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CKS1B | P61024 | 14/20 | 0.64 |
| ▸ | SKP2 | Q13309 | 14/20 | 0.64 |
| ▸ | COMT | P21964 | 1/20 | 0.49 |
| ▸ | GLO1 | Q04760 | 3/20 | 0.44 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.43 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21869672 | 0.89 | CKS1B (0.62) | CKS1BSKP2COMTGLO1MEN1 | |
| SCHEMBL21869662 | 0.88 | CKS1B (0.60) | CKS1BSKP2GLO1DYRK1ADYRK1B | |
| SCHEMBL21869721 | 0.87 | CKS1B (0.66) | CKS1BSKP2GLO1 | |
| SCHEMBL21869806 | 0.85 | CKS1B (0.69) | CKS1BSKP2GLO1KMT2A | |
| SCHEMBL21869665 | 0.84 | CKS1B (0.66) | CKS1BSKP2COMTGLO1MEN1 | |
| SCHEMBL21869643 | 0.81 | CKS1B (0.59) | CKS1BSKP2GLO1 | |
| SCHEMBL21869666 | 0.79 | CKS1B (0.59) | CKS1BSKP2GLO1 | |
| SCHEMBL21869726 | 0.79 | CKS1B (0.58) | CKS1BSKP2COMTMEN1KMT2A | |
| SCHEMBL21869712 | 0.79 | CKS1B (0.64) | CKS1BSKP2COMTGLO1MEN1 | |
| SCHEMBL17506518 | 0.78 | CKS1B (1.00) | CKS1BSKP2MEN1KMT2ATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3180328-B1 | QUINOLINE DERIVATIVES USEFUL AS UBIQUITINATION INHIBITORS | RIGEL PHARMACEUTICALS INC (US) | 2020-03-18 | — | — | EP | disclosed |