Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CKS1B | P61024 | 13/20 | 0.62 |
| ▸ | SKP2 | Q13309 | 13/20 | 0.62 |
| ▸ | GLO1 | Q04760 | 7/20 | 0.46 |
| ▸ | COMT | P21964 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21869707 | 0.90 | CKS1B (0.62) | CKS1BSKP2GLO1COMT | |
| SCHEMBL21869671 | 0.87 | CKS1B (0.64) | CKS1BSKP2GLO1 | |
| SCHEMBL17506541 | 0.77 | CKS1B (1.00) | CKS1BSKP2GLO1 | |
| SCHEMBL21869666 | 0.76 | CKS1B (0.59) | CKS1BSKP2GLO1 | |
| SCHEMBL17506532 | 0.73 | CKS1B (0.82) | CKS1BSKP2GLO1 | |
| SCHEMBL21869667 | 0.73 | CKS1B (0.65) | CKS1BSKP2GLO1 | |
| SCHEMBL21869715 | 0.71 | CKS1B (0.64) | CKS1BSKP2GLO1COMT | |
| SCHEMBL21869705 | 0.69 | CKS1B (0.68) | CKS1BSKP2GLO1 | |
| SCHEMBL17506530 | 0.69 | CKS1B (1.00) | CKS1BSKP2GLO1 | |
| SCHEMBL21869643 | 0.68 | CKS1B (0.59) | CKS1BSKP2GLO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3180328-B1 | QUINOLINE DERIVATIVES USEFUL AS UBIQUITINATION INHIBITORS | RIGEL PHARMACEUTICALS INC (US) | 2020-03-18 | — | — | EP | disclosed |