SCHEMBL21870

SCHEMBL21870

Cc1cc(C)c(C(=O)O)c(C)c1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 4/20 0.55
L3MBTL1 Q9Y468 1/20 0.55
CYP3A4 P08684 2/20 0.54
ACHE P22303 1/20 0.54
TPMT P51580 1/20 0.52
ALDH1A1 P00352 2/20 0.50
SMN1; SMN2 Q16637 2/20 0.50
MAPK1 P28482 1/20 0.50
MAPT P10636 1/20 0.45
HCAR1 Q9BXC0 1/20 0.44
NOTUM Q6P988 1/20 0.44
LDHA P00338 1/20 0.43
LDHB P07195 1/20 0.43
POLB P06746 1/20 0.43
TAS1R3 Q7RTX0 2/20 0.42
TAS1R1 Q7RTX1 2/20 0.42
TAS1R2 Q8TE23 2/20 0.42
IGFBP3 P17936 1/20 0.42
KMT2A Q03164 2/20 0.41
RXRA P19793 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL377596 1.00 KDM4E (0.55) KDM4EL3MBTL1CYP3A4ACHETPMT
SCHEMBL6916749 0.97 KDM4E (0.53) KDM4EL3MBTL1CYP3A4ACHETPMT
SCHEMBL6915288 0.97 KDM4E (0.53) KDM4EL3MBTL1CYP3A4ACHETPMT
Hydrochloric Acid SCHEMBL5167636 0.97 KDM4E (0.53) KDM4EL3MBTL1CYP3A4ACHETPMT
SCHEMBL6917032 0.97 KDM4E (0.53) KDM4EL3MBTL1CYP3A4ACHETPMT
SCHEMBL17558193 0.97 KDM4E (0.53) KDM4EL3MBTL1CYP3A4ACHETPMT
SCHEMBL6915449 0.97 KDM4E (0.53) KDM4EL3MBTL1CYP3A4ACHETPMT
SCHEMBL6912557 0.97 KDM4E (0.53) KDM4EL3MBTL1CYP3A4ACHETPMT
SCHEMBL6912704 0.97 KDM4E (0.53) KDM4EL3MBTL1CYP3A4ACHETPMT
SCHEMBL6916700 0.97 KDM4E (0.53) KDM4EL3MBTL1CYP3A4ACHETPMT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 9986 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260035402-A1 C10-ALKYLENE SUBSTITUTED 13-MEMBERED MACROLIDES AND USES THEREOF ZIKANI THERAPEUTICS INC (US) 2026-02-05 US claimed
EP-4661890-A1 PTP1B/TC-PTP DUAL INHIBITORS AND PROTEIN DEGRADERS Purdue Research Foundation (US) 2025-12-17 EP claimed
EP-3947382-B1 COMPOUNDS FOR USES IN PHARMACOLOGICAL INDUCTION OF HBF FOR TREATMENT OF SICKLE CELL DISEASE AND BETA-THALASSEMIA ACADEMIA SINICA (TW) 2025-09-24 EP claimed
CN-119591544-A Dual hydrocarbon activation strategy for synthesis of novel unnatural amino acids and polypeptides 南京林业大学 2025-03-11 CN claimed
CN-116836180-B Nitrogen and oxygen hetero-polycyclic aromatic hydrocarbon and synthetic method and application thereof 河南农业大学 2025-03-11 CN claimed
US-20250066616-A1 A rosin polymer to be used as inert component in a coating, in particular a radiation curing coating such as a radiation curing printing ink HUBERGROUP DEUTSCHLAND GMBH (DE) 2025-02-27 US claimed
CN-119059909-A Method for preparing tert-butyl acrylate by palladium-catalyzed acetylene gas carbonylation reaction 华东理工大学 2024-12-03 CN claimed
CN-119040670-A Gallium extraction agent, preparation method thereof and gallium extraction method 矿冶科技集团有限公司 2024-11-29 CN claimed
CN-118580159-A Synthesis method of nitrogen heterocyclic aromatic hydrocarbon modified beta-amino acid ester 国科大杭州高等研究院 2024-09-03 CN claimed
WO-2024167565-A1 PTP1B/TC-PTP DUAL INHIBITORS AND PROTEIN DEGRADERS PURDUE RESEARCH FOUNDATION (US) 2024-08-15 WO claimed
EP-0273489-A2 Process for the selective preparation of alkenecarboxylic acid derivatives SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) 1988-07-06 EP claimed
CN-87107325-A Selective preparation of alkene carboxylic acid derivatives 1988-06-22 CN claimed
EP-0083224-B1 PROCESS FOR PRODUCING AROMATIC POLYCARBOXYLIC ACID WITH HIGH PURITY MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 1987-05-27 EP claimed
EP-0169650-A2 Process for preparing aromatic urethanes from nitroaromatic compounds Montedison S.p.A. (IT) 1986-01-29 EP claimed
US-4519996-A USING MACROMOLECULES OF OPEN-CHAIN POLYETHERS OR CROWN COMPOUNDS KERNFORSCHUNGSZENTRUM KARLSRUHE GMBH (DE) 1985-05-28 US claimed
EP-0083224-A1 Process for producing aromatic polycarboxylic acid with high purity MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 1983-07-06 EP claimed
US-4357257-A Low viscosity slurry and method of preparing same PHILLIPS PETROLEUM COMPANY (US) 1982-11-02 US claimed
US-4346232-A CATALYTIC OXIDATION OF POLYALKYL-SUBSTITUTED AROMATIC ALDEHYDE OR ACID MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 1982-08-24 US claimed
US-4228302-A Process for preparing a methyl-substituted benzaldehyde E. I. DUPONT DE NEMOURS AND COMPANY (US) 1980-10-14 US claimed
US-4154921-A REDUCE FORMATION OF SCALE BY ADDITION OF A HINDERED BENZOIC ACID INCLUDING 2,6-DICHLORO-, 2,6-DIMETHYL-, AND 2,4,6-TRIMETHYL-/; E. I. DU PONT DE NEMOURS AND COMPANY (US) 1979-05-15 US claimed