Cyclohexanone

Cyclohexanone

SCHEMBL2187097

C=O.N.O=C1CCCCC1

nearest known ligand 0.79

Full drug profile on Sugi Atlas →

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
TRIM24 O15164 2/20 0.79
TRIM33 Q9UPN9 2/20 0.79
ALDH1A1 P00352 1/20 0.79
KMT2A Q03164 1/20 0.32
CA1 P00915 1/20 0.30
CA9 Q16790 1/20 0.30
FKBP5 Q13451 1/20 0.30
CRBN Q96SW2 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Cycloheptanone SCHEMBL28101629 0.96 TRIM24 (0.85) TRIM24TRIM33ALDH1A1KMT2ACA1
Cyclohexanone SCHEMBL2487748 0.96
Cyclononanone SCHEMBL28385702 0.93 TRIM24 (0.92) TRIM24TRIM33ALDH1A1KMT2ACA1
Cyclohexanone SCHEMBL4843445 0.93
Cycloheptanone SCHEMBL28833619 0.93
Cycloheptanone SCHEMBL27306619 0.89 TRIM24 (0.85) TRIM24TRIM33ALDH1A1KMT2ACA1
Cyclohexanone SCHEMBL27538743 0.89
Cyclohexanone SCHEMBL3671904 0.89
SCHEMBL25380098 0.89 TRIM24 (1.00) TRIM24TRIM33ALDH1A1KMT2ACA1
Cyclohexanone SCHEMBL713141 0.89

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1831167-B1 LIQUID PHASE PROCESS FOR THE SYNTHESIS OF ANNULATED PYRIDINES OVER ZEOLITE TYPE MOLECULAR SIEVE CATALYSTS COUNCIL SCIENT IND RES (IN) 2011-07-13 EP disclosed
US-7491828-B2 Liquid phase process for the synthesis of annulated pyridines over molecular sieve catalysts COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) 2009-02-17 US disclosed
US-20060149068-A1 Liquid phase process for the synthesis of annulated pyridines over molecular sieve catalysts COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) 2006-07-06 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060149068-A1 Liquid phase process for the synthesis of annulated pyridines over molecular sieve catalysts AURKA, CDK4, SKP2 TRIM24 1413/4885TRIM33 1865/4885ALDH1A1 255/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.