Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SHH | Q15465 | 11/20 | 1.00 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Robotnikinin SCHEMBL2187345 | 1.00 | SHH (1.00) | SHH | |
| Robotnikinin SCHEMBL12417975 | 1.00 | SHH (1.00) | SHH | |
| Robotnikinin SCHEMBL12417981 | 1.00 | SHH (1.00) | SHH | |
| Robotnikinin SCHEMBL12417978 | 1.00 | SHH (1.00) | SHH | |
| Robotnikinin SCHEMBL10063512 | 1.00 | SHH (1.00) | SHH | |
| Robotnikinin SCHEMBL10029768 | 1.00 | SHH (1.00) | SHH | |
| SCHEMBL17497657 | 0.95 | SHH (1.00) | SHH | |
| SCHEMBL17497661 | 0.95 | SHH (1.00) | SHH | |
| SCHEMBL17517675 | 0.94 | SHH (0.88) | SHH | |
| SCHEMBL17515414 | 0.94 | SHH (0.88) | SHH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 61 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2026089602-A1 | IMPROVED METHOD FOR GENERATING INNER EAR ORGANOIDS | ACADEMISCH ZIEKENHUIS LEIDEN (h.o.d.n. LUMC) (NL) | 2026-04-30 | — | — | WO | claimed |
| US-20240390305-A1 | METHODS FOR TREATING AORTIC VALVE STENOSIS WITH A HEDGEHOG PATHWAY INHIBITOR | THE TRUSTEES OF INDIANA UNIVERSITY (US) | 2024-11-28 | — | — | US | claimed |
| WO-2024035132-A1 | METHOD FOR SELECTIVE DIFFERENTIATION INTO DORSAL-METENCEPHALIC TISSUE FROM EMBRYOID DERIVED FROM PLURIPOTENT STEM CELL | 주식회사 넥스트앤바이오 | 2024-02-15 | — | — | WO | claimed |
| CN-116870166-A | Shh pathway for modulating biological rhythms and related applications thereof | 中国人民解放军军事科学院军事医学研究院 | 2023-10-13 | — | — | CN | claimed |
| CN-115463218-B | Shh pathway for modulating biological rhythms and related applications thereof | 中国人民解放军军事科学院军事医学研究院 | 2023-07-14 | — | — | CN | claimed |
| US-20220354832-A1 | METHODS FOR TREATING AORTIC VALVE STENOSIS WITH A HEDGEHOG PATHWAY INHIBITOR | THE TRUSTEES OF INDIANA UNIVERSITY (US) | 2022-11-10 | — | — | US | claimed |
| US-11459547-B2 | Method for producing osteoblast cluster using human iPS cells | TOHOKU UNIVERSITY (JP) | 2022-10-04 | — | — | US | claimed |
| US-20220145255-A1 | METHOD FOR PRODUCING OSTEOBLAST CLUSTER USING IPS CELLS | TOHOKU UNIVERSITY (JP) | 2022-05-12 | — | — | US | claimed |
| WO-2026089602-A1 | IMPROVED METHOD FOR GENERATING INNER EAR ORGANOIDS | ACADEMISCH ZIEKENHUIS LEIDEN (h.o.d.n. LUMC) (NL) | 2026-04-30 | — | — | WO | disclosed |
| EP-4642465-A1 | A CANCER ASSOCIATED FIBROBLAST (CAF) INHIBITOR FOR USE WITH AN ALTERNATING ELECTRIC FIELD IN A METHOD OF TREATING DISEASES SUCH AS CANCER | Novocure GmbH (CH) | 2025-11-05 | — | — | EP | disclosed |
| WO-2025217286-A1 | STEM CELL DERIVED ASTROCYTES AND RELATED METHODS OF USE AND PRODUCTION | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2025-10-16 | — | — | WO | disclosed |
| US-20250295583-A1 | INHALED HEDGEHOG INHIBITORS | WBX PHARMA, INC. | 2025-09-25 | — | — | US | disclosed |
| EP-4529468-A1 | FORMULATION OF API'S AND EXCIPIENT'S IN AN ICELL VIA HYDROPHOBIC ION PAIRING | Danmarks Tekniske Universitet (DK) | 2025-04-02 | — | — | EP | disclosed |
| EP-4529477-A1 | POROUS EXPANDING BIOCOMPATIBLE SCAFFOLDS | Danmarks Tekniske Universitet (DK) | 2025-04-02 | — | — | EP | disclosed |
| US-20120082623-A1 | SHH Regulation and Methods Thereof | NATIONAL INSTITUTES OF HEALTH - DIRECTOR DEITR | 2012-04-05 | — | — | US | disclosed |
| US-20110172233-A1 | SONIC HEDGEHOG MODULATORS | MASSACHUSETTS INSTITUTE OF TECHNOLOGY | 2011-07-14 | — | — | US | disclosed |
| US-20110172233-A1 | SONIC HEDGEHOG MODULATORS | MASSACHUSETTS INSTITUTE OF TECHNOLOGY | 2011-07-14 | — | — | US | disclosed |
| US-20110172233-A1 | SONIC HEDGEHOG MODULATORS | MASSACHUSETTS INSTITUTE OF TECHNOLOGY | 2011-07-14 | — | — | US | disclosed |
| WO-2009132032-A2 | SONIC HEDGEHOG MODULATORS | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2009-10-29 | — | — | WO | disclosed |
| WO-2009132032-A2 | SONIC HEDGEHOG MODULATORS | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2009-10-29 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120082623-A1 | SHH Regulation and Methods Thereof | SHH, CHAT, GLI1 | SHH 1/4885 |
| US-20110172233-A1 | SONIC HEDGEHOG MODULATORS | SHH, GLI1, SMO | SHH 1/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.