Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP4K4 | O95819 | 20/20 | 0.76 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15537863 | 0.87 | MAP4K4 (1.00) | MAP4K4 | |
| SCHEMBL15536275 | 0.82 | MAP4K4 (1.00) | MAP4K4 | |
| SCHEMBL15587803 | 0.80 | MAP4K4 (1.00) | MAP4K4 | |
| SCHEMBL15587240 | 0.78 | MAP4K4 (1.00) | MAP4K4 | |
| SCHEMBL15587785 | 0.78 | MAP4K4 (1.00) | MAP4K4 | |
| SCHEMBL15587869 | 0.75 | MAP4K4 (1.00) | MAP4K4 | |
| SCHEMBL15587460 | 0.74 | MAP4K4 (1.00) | MAP4K4 | |
| SCHEMBL15538115 | 0.73 | MAP4K4 (1.00) | MAP4K4 | |
| SCHEMBL15537046 | 0.73 | MAP4K4 (0.85) | MAP4K4 | |
| SCHEMBL15587621 | 0.73 | MAP4K4 (0.80) | MAP4K4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2855459-B1 | AMINOQUINAZOLINE AND PYRIDOPYRIMIDINE DERIVATIVES | HOFFMANN LA ROCHE (CH) | 2020-04-29 | — | — | EP | claimed |