SCHEMBL21874992

SCHEMBL21874992

OC[C@H]1OC(n2cnc3c(NCc4ccc(O)c(O)c4)ncnc32)C[C@@H]1O

nearest known ligand 0.71

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
PRKAG1 P54619 1/20 0.71
PRKAA1 Q13131 1/20 0.71
PRKAB1 Q9Y478 1/20 0.71
SLC29A1 Q99808 2/20 0.71
HIF1A Q16665 1/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12579649 0.91 SLC29A1 (0.66) PRKAG1PRKAA1PRKAB1SLC29A1HIF1A
SCHEMBL19582973 0.91 SLC29A1 (0.66) PRKAG1PRKAA1PRKAB1SLC29A1HIF1A
SCHEMBL20626491 0.91 SLC29A1 (0.66) PRKAG1PRKAA1PRKAB1SLC29A1HIF1A
SCHEMBL14713448 0.91 SLC29A1 (0.66) PRKAG1PRKAA1PRKAB1SLC29A1HIF1A
SCHEMBL19583030 0.90 SLC29A1 (0.65) PRKAG1PRKAA1PRKAB1SLC29A1HIF1A
SCHEMBL19582971 0.90 SLC29A1 (0.77) PRKAG1PRKAA1PRKAB1SLC29A1HIF1A
SCHEMBL19583026 0.88 SLC29A1 (0.68) PRKAG1PRKAA1PRKAB1SLC29A1
SCHEMBL19583075 0.88 SLC29A1 (0.69) PRKAG1PRKAA1PRKAB1SLC29A1HIF1A
SCHEMBL13467483 0.87 SLC29A1 (0.76) SLC29A1HIF1A
SCHEMBL20626371 0.87 SLC29A1 (0.76) SLC29A1HIF1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3229772-B1 6-ARYL-9-GLYCOSYLPURINES AND USE THEREOF UNIV PALACKEHO (CZ) 2020-04-29 EP claimed