SCHEMBL218758

SCHEMBL218758

Nc1ccncc1O

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30015578 1.00
Hydrochloric Acid SCHEMBL31519177 0.97
Methane SCHEMBL15389723 0.97
Sulfuric Acid SCHEMBL1712934 0.89 EP300 (0.46)
Dimethylcarbate SCHEMBL8375856 0.82 KDM4C (0.50)
SCHEMBL144048 0.79
SCHEMBL8375129 0.77 KDM4E (0.45)
Hydrochloric Acid SCHEMBL5308964 0.77
Amifampridine SCHEMBL21273 0.75
SCHEMBL2283975 0.75

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 295 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12268677-B2 4-aminopyridine (4-AP) and bone morphogenetic protein 2 (BMP-2) THE PENN STATE RESEARCH FOUNDATION (US) 2025-04-08 US claimed
CN-119463682-A Dual self-repairing polyurethane coating and preparation method thereof 万华化学集团股份有限公司 2025-02-18 CN claimed
US-20230058178-A1 METHODS AND MATERIALS FOR TREATING NERVE INJURY AND/OR PROMOTING WOUND HEALING UNITED STATES GOVERNMENT 2023-02-23 US claimed
EP-4093484-A1 METHODS AND MATERIALS FOR TREATING NERVE INJURY AND/OR PROMOTING WOUND HEALING THE PENN STATE RESEARCH FOUNDATION (US) 2022-11-30 EP claimed
WO-2021150773-A1 METHODS AND MATERIALS FOR TREATING NERVE INJURY AND/OR PROMOTING WOUND HEALING THE PENN STATE RESEARCH FOUNDATION (US) 2021-07-29 WO claimed
CN-113122053-A Quantum dot ink and preparation method of quantum dot film TCL集团股份有限公司 2021-07-16 CN claimed
EP-3802547-A1 PROCESS FOR PRODUCING COMPOUNDS CONTAINING AN OXAZOLOPYRIDINONE FUNCTIONAL GROUP Biocidal Alternative Solutions (BE) 2021-04-14 EP claimed
WO-2017120298-A1 TREATMENT OF RADICULOPATHIES WITH 4-AMINOPYRIDINE OR DERIVATIVES THEREOF UNIVERSITY OF ROCHESTER (US) 2017-07-13 WO claimed
US-20130330277-A1 METHODS OF USING SUSTAINED RELEASE AMINOPYRIDINE COMPOSITIONS ACORDA THERAPEUTICS, INC. (US) 2013-12-12 US claimed
US-20130072527-A1 METHODS OF USING SUSTAINED RELEASE AMINOPYRIDINE COMPOSITIONS ACORDA THERAPEUTICS, INC. (US) 2013-03-21 US claimed
EP-2343976-A1 METHODS OF USING SUSTAINED RELEASE AMINOPYRIDINE COMPOSITIONS Acorda Therapeutics, Inc. (US) 2011-07-20 EP claimed
CN-101827522-A Continue to discharge the using method of aminopyridine compositions ACORDA THERAPEUTICS INC 2010-09-08 CN claimed
WO-2010030755-A1 METHODS OF USING SUSTAINED RELEASE AMINOPYRIDINE COMPOSITIONS ACORDA THERAPEUTICS, INC. (US) 2010-03-18 WO claimed
US-20100061935-A1 METHODS OF USING SUSTAINED RELEASE AMINOPYRIDINE COMPOSITIONS ACORDA THERAPEUTICS, INC. (US) 2010-03-11 US claimed
JP-4261157-A None JP disclosed
US-20260022130-A1 HETEROCYCLIC COMPOUNDS AS MONOACYLGLYCEROL LIPASE INHIBITORS HOFFMANN-LA ROCHE INC. (US) 2026-01-22 US disclosed
EP-4648773-A1 POTASSIUM CHANNEL BLOCKERS OR DERIVATIVES THEREOF FOR PREVENTING, ALLEVIATING, AND/OR TREATING MORBIDITY AND MORTALITY INDUCED BY PATHOGENS OR OTHER INDUCERS OF IMMUNE EXHAUSTION AND/OR EXCESS IMMUNE ACTIVATION University of Rochester (US) 2025-11-19 EP disclosed
JP-H04261157-A SUBSTITUTED-4-AMINO-3-PYRIDINOL, ITS PRODUCTION AND ITS USE AS MEDICAMENT HOECHST ROUSSEL PHARMACEUT INC 1992-09-17 JP disclosed
EP-0477903-A2 Substituted-4-amino-3-pyridinols, a process for their preparation and their use as medicaments HOECHST-ROUSSEL PHARMACEUTICALS INCORPORATED (US) 1992-04-01 EP disclosed
US-3935195-A FLUORESCENT DYE STERLING DRUG INC. (US) 1976-01-27 US disclosed