Known targets — ChEMBL curated mechanism
MMP1MMP13MMP7MMP8polrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Fructose. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C9 | P11712 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | PDE4A | P27815 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Fructose SCHEMBL2405711 | 1.00 | CYP2C9 (0.52) | CYP2C9TSHRPDE4ALMNAL3MBTL1 | |
| Fructose SCHEMBL10760647 | 1.00 | CYP2C9 (0.52) | CYP2C9TSHRPDE4ALMNAL3MBTL1 | |
| Fructose SCHEMBL27513529 | 1.00 | CYP2C9 (0.52) | CYP2C9TSHRPDE4ALMNAL3MBTL1 | |
| Fructose SCHEMBL2956819 | 1.00 | CYP2C9 (0.52) | CYP2C9TSHRPDE4ALMNAL3MBTL1 | |
| Fructose SCHEMBL9769463 | 0.98 | CYP2C9 (0.50) | CYP2C9TSHRPDE4ALMNAL3MBTL1 | |
| Fructose SCHEMBL4736429 | 0.95 | CYP2C9 (0.52) | CYP2C9TSHRPDE4ALMNAL3MBTL1 | |
| Fructose SCHEMBL15538035 | 0.94 | CYP2C9 (0.47) | CYP2C9TSHRPDE4ALMNAL3MBTL1 | |
| Fructose SCHEMBL9788519 | 0.93 | CYP2C9 (0.54) | CYP2C9TSHRPDE4ALMNAL3MBTL1 | |
| Fructose SCHEMBL6244358 | 0.93 | CYP2C9 (0.54) | CYP2C9TSHRPDE4ALMNAL3MBTL1 | |
| Fructose SCHEMBL27309110 | 0.93 | CYP2C9 (0.54) | CYP2C9TSHRPDE4ALMNAL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 807 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110506879-A | A kind of solid beverage and its preparation method for alleviating visual fatigue | ACC QUALITY DETECTION TECH SHANGHAI CO LTD | 2019-11-29 | — | — | CN | claimed |
| CN-110373342-A | Lactobacillus reuteri and application thereof | 深圳市华大农业应用研究院 | 2019-10-25 | — | — | CN | claimed |
| CN-110357898-A | A method of reducing sorbitol acetal fusing point | 广州精至百特利化工科技有限公司 | 2019-10-22 | — | — | CN | claimed |
| CN-110250244-A | A kind of cake and its manufacture craft | 陆泓企 | 2019-09-20 | — | — | CN | claimed |
| CN-110221031-A | The measuring method of sour odour material sense organ acidity under a kind of sweet substance background | 浙江工商大学 | 2019-09-10 | — | — | CN | claimed |
| CN-110200869-A | A kind of anti-flu herbal medicine toothpaste of Radix Isatidis | 汪洪涛 | 2019-09-06 | — | — | CN | claimed |
| CN-110208471-A | The measuring method of sweet substance sense organ sugariness under a kind of sour odour material background | 浙江工商大学 | 2019-09-06 | — | — | CN | claimed |
| CN-110140820-A | A kind of perinatal period sow nutrition fortifier and its preparation method and application | 四川铁骑力士实业有限公司 | 2019-08-20 | — | — | CN | claimed |
| CN-110139568-A | The method and composition of the crude preparation of reinforcement sugar for glycemic control | 快乐糖果有限公司 | 2019-08-16 | — | — | CN | claimed |
| CN-110049866-A | Polyoxometallic acid salt complex and its application in cancer treatment | 爱默蕾大学 | 2019-07-23 | — | — | CN | claimed |
| CN-106272035-A | A kind of grinding pad of gallium oxide single crystal and preparation method thereof | 盐城工学院 | 2017-01-04 | — | — | CN | claimed |
| CN-106221254-A | A kind of Caulis et Folium Oryzae Plant fiber's synthetic resin and preparation technology thereof | 安徽科邦树脂科技有限公司 | 2016-12-14 | — | — | CN | claimed |
| CN-103826567-B | The ampoule for conserving species implant of humidity can be kept | OSSTEMIMPLANT Co.,Ltd. (KR) | 2016-11-30 | — | — | CN | claimed |
| CN-106132400-A | Composition for treating ulcerative colitis | 希格默伊德药业有限公司 | 2016-11-16 | — | — | CN | claimed |
| CN-104144963-B | There is the reactive epoxy resin being derived from biology of improvement | 蒙彼利埃第二大学 | 2016-10-26 | — | — | CN | claimed |
| CN-106047747-A | High-temperature resistant bacillus amyloliquefaciens YTK1 and application thereof in tobacco leaf curing | 中国烟草总公司广东省公司 | 2016-10-26 | — | — | CN | claimed |
| CN-103520248-B | A kind of Maca chewing gum and its preparation method and application | 云南白药集团股份有限公司 | 2016-10-12 | — | — | CN | claimed |
| CN-104476017-B | A kind of lead-free solder scaling powder and preparation method thereof | 兑元工业科技（惠州）有限公司 | 2016-09-21 | — | — | CN | claimed |
| CN-105919849-A | Emulsified whitening and cleaning cream containing mulberry barks | 刘学勤 | 2016-09-07 | — | — | CN | claimed |
| CN-105851437-A | Honeysuckle throat clearing and moistening sugar and preparation method thereof | 李东荣 | 2016-08-17 | — | — | CN | claimed |