Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19644592 | 0.87 | HIF1A (0.30) | HIF1A | |
| SCHEMBL19644580 | 0.87 | HIF1A (0.30) | HIF1A | |
| SCHEMBL24591624 | 0.83 | HIF1A (0.31) | HIF1A | |
| SCHEMBL21880508 | 0.83 | HIF1A (0.31) | HIF1A | |
| SCHEMBL24591621 | 0.83 | HIF1A (0.31) | HIF1A | |
| SCHEMBL19644589 | 0.83 | — | — | |
| SCHEMBL24591619 | 0.77 | — | — | |
| SCHEMBL21137110 | 0.76 | HIF1A (0.33) | HIF1A | |
| SCHEMBL21880798 | 0.74 | HIF1A (0.36) | HIF1A | |
| SCHEMBL17453462 | 0.74 | HIF1A (0.36) | HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3174870-B1 | THIENO [3,2-D]PYRIMIDINES, FURO [3,2,D]PYRIMIDINES AND PYRROLO [3,2-D]PYRIMIDINES USEFUL FOR TREATING RESPIRATORY SYNCITIAL VIRUS INFECTIONS | GILEAD SCIENCES INC (US) | 2020-04-15 | — | — | EP | disclosed |