Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAS1 | P04201 | 1/20 | 0.60 |
| ▸ | AGTR2 | P50052 | 13/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | GMNN | O75496 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.38 |
| ▸ | APEX1 | P27695 | 1/20 | 0.38 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | THPO | P40225 | 1/20 | 0.38 |
| ▸ | MTOR | P42345 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1334134 | 0.90 | MAS1 (0.74) | MAS1AGTR2MEN1GMNNUSP2 | |
| SCHEMBL29701254 | 0.89 | MAS1 (0.73) | MAS1AGTR2MEN1GMNNUSP2 | |
| SCHEMBL3975878 | 0.89 | MAS1 (0.73) | MAS1AGTR2MEN1GMNNUSP2 | |
| Tromethamine SCHEMBL3912101 | 0.86 | MAS1 (0.69) | MAS1AGTR2MEN1GMNNUSP2 | |
| SCHEMBL4102363 | 0.83 | MAS1 (0.67) | MAS1AGTR2MEN1GMNNUSP2 | |
| SCHEMBL3906331 | 0.82 | MAS1 (0.68) | MAS1AGTR2MEN1GMNNUSP2 | |
| Lysine SCHEMBL3906133 | 0.82 | MAS1 (0.63) | MAS1AGTR2MEN1GMNNUSP2 | |
| SCHEMBL3908044 | 0.81 | MAS1 (0.69) | MAS1AGTR2MEN1GMNNUSP2 | |
| SCHEMBL3915251 | 0.80 | MAS1 (0.69) | MAS1AGTR2MEN1GMNNUSP2 | |
| SCHEMBL4099345 | 0.79 | MAS1 (0.66) | MAS1AGTR2MEN1GMNNUSP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4284779-A1 | METHODS AND AGENTS THAT STIMULATE MITOCHONDRIAL TURNOVER FOR TREATING DISEASE | Capacity Bio, Inc. (US) | 2023-12-06 | — | — | EP | disclosed |
| EP-2341938-A2 | USE OF AN ANG-(1-7) RECEPTOR AGONIST IN ACUTE LUNG INJURY | Charité - Universitätsmedizin Berlin (DE) | 2011-07-13 | — | — | EP | disclosed |
| WO-2010028845-A2 | USE OF AN ANG-(1-7) RECEPTOR AGONIST IN ACUTE LUNG INJURY | CHARITÉ - UNIVERSITÄTSMEDIZIN BERLIN (DE) | 2010-03-18 | — | — | WO | disclosed |