Known targets — ChEMBL curated mechanism
ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Bromoacetic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromoacetic Acid SCHEMBL8058549 | 1.00 | TSHR (0.77) | — | |
| Bromoacetic Acid SCHEMBL27970639 | 0.96 | TSHR (0.71) | — | |
| Bromoacetic Acid SCHEMBL28235321 | 0.92 | — | — | |
| Bromoacetic Acid SCHEMBL11212568 | 0.90 | TSHR (0.62) | — | |
| Bromoacetic Acid SCHEMBL27709869 | 0.89 | — | — | |
| Bromoacetic Acid SCHEMBL15646451 | 0.88 | — | — | |
| Bromoacetic Acid SCHEMBL1645768 | 0.88 | — | — | |
| Bromoacetic Acid SCHEMBL1332132 | 0.88 | — | — | |
| Bromoacetic Acid SCHEMBL1332313 | 0.88 | — | — | |
| Bromoacetic Acid SCHEMBL1332022 | 0.88 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111936484-A | Chromenopyridine derivatives as inhibitors of phosphatidylinositol phosphokinase | 拉文纳制药公司 | 2020-11-13 | — | — | CN | disclosed |
| US-8450543-B2 | Integrated methods of preparing renewable chemicals | GEVO, INC. (US) | 2013-05-28 | — | — | US | disclosed |
| US-20110172475-A1 | INTEGRATED METHODS OF PREPARING RENEWABLE CHEMICALS | GEVO, INC. (US) | 2011-07-14 | — | — | US | disclosed |