Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CFTR | P13569 | 11/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.38 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.34 |
| ▸ | CTNNB1 | P35222 | 2/20 | 0.34 |
| ▸ | WNT3A | P56704 | 2/20 | 0.34 |
| ▸ | PDE2A | O00408 | 1/20 | 0.33 |
| ▸ | GPR183 | P32249 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL350025 | 0.82 | PDE2A (0.39) | CFTRPDE2A | |
| Water SCHEMBL2201519 | 0.79 | PDE2A (0.37) | CFTRCTNNB1WNT3APDE2A | |
| SCHEMBL28409092 | 0.79 | PDE2A (0.37) | CFTRSLC6A4SLC6A3PDE2A | |
| SCHEMBL21820651 | 0.79 | SLC6A4 (0.37) | CFTRSLC6A4SLC6A3PDE2A | |
| SCHEMBL22099906 | 0.76 | CFTR (0.36) | CFTRSMYD3CTNNB1WNT3APDE2A | |
| SCHEMBL21961921 | 0.74 | PDE2A (0.36) | CFTRSLC6A4SLC6A3CTNNB1WNT3A | |
| SCHEMBL4620287 | 0.73 | CFTR (0.44) | CFTR | |
| SCHEMBL21820755 | 0.73 | PDE4A (0.37) | CFTRCTNNB1WNT3APDE2A | |
| SCHEMBL13887044 | 0.71 | MEN1 (0.46) | — | |
| SCHEMBL17644323 | 0.70 | PIK3CA (0.39) | CFTRSMYD3CTNNB1WNT3APDE2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10961266-B2 | Chemoselective methylene hydroxylation in aromatic molecules | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 2021-03-30 | — | — | US | disclosed |
| US-20200087331-A1 | CHEMOSELECTIVE METHYLENE HYDROXYLATION IN AROMATIC MOLECULES | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS | 2020-03-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10961266-B2 | Chemoselective methylene hydroxylation in aromatic molecules | PAH, DBH, AHR | CFTR 4476/4885SLC6A4 2694/4885SLC6A3 290/4885 |
| US-20200087331-A1 | CHEMOSELECTIVE METHYLENE HYDROXYLATION IN AROMATIC MOLECULES | PAH, DBH, AHR | CFTR 4476/4885SLC6A4 2694/4885SLC6A3 290/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.