⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27287586 | 1.00 | — | — | |
| SCHEMBL27287585 | 1.00 | — | — | |
| SCHEMBL19113387 | 0.77 | TSHR (0.36) | — | |
| SCHEMBL7731856 | 0.77 | TSHR (0.43) | — | |
| SCHEMBL22631157 | 0.77 | TSHR (0.43) | — | |
| SCHEMBL11371461 | 0.75 | TSHR (0.34) | — | |
| SCHEMBL6818237 | 0.74 | — | — | |
| SCHEMBL19258431 | 0.74 | — | — | |
| SCHEMBL27280594 | 0.74 | TSHR (0.48) | — | |
| SCHEMBL27281036 | 0.74 | TSHR (0.48) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024081311-A1 | CBL-B MODULATORS AND USES THEREOF | NIMBUS CLIO, INC. (US) | 2024-04-18 | — | — | WO | disclosed |
| WO-2024076670-A2 | TETHERED HETEROCYCLIC INHIBITORS OF KRAS G12C MUTANT PROTEINS AND USES THEREOF | AMGEN INC. (US) | 2024-04-11 | — | — | WO | disclosed |
| EP-3632944-A1 | POLYMERS AND DNA COPOLYMER COATINGS | Illumina Cambridge Limited (GB) | 2020-04-08 | — | — | EP | disclosed |