Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 15/20 | 0.38 |
| ▸ | CNR1 | P21554 | 10/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21191600 | 1.00 | CNR2 (0.38) | CNR2CNR1TDP1L3MBTL1KCNH2 | |
| SCHEMBL21191796 | 1.00 | CNR2 (0.38) | CNR2CNR1TDP1L3MBTL1KCNH2 | |
| SCHEMBL19738702 | 0.98 | CNR2 (0.37) | CNR2CNR1TDP1L3MBTL1 | |
| SCHEMBL18869370 | 0.98 | CNR2 (0.37) | CNR2CNR1TDP1L3MBTL1 | |
| SCHEMBL22024290 | 0.98 | CNR2 (0.36) | CNR2CNR1TDP1L3MBTL1 | |
| SCHEMBL21718495 | 0.93 | CNR2 (0.36) | CNR2CNR1TDP1L3MBTL1 | |
| SCHEMBL19738148 | 0.93 | ESR1 (0.35) | CNR2CNR1TDP1L3MBTL1 | |
| SCHEMBL19738659 | 0.90 | ESR1 (0.33) | CNR2CNR1 | |
| SCHEMBL19738625 | 0.86 | ESR1 (0.33) | CNR2CNR1 | |
| SCHEMBL19738629 | 0.86 | CNR2 (0.47) | CNR2CNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230075221-A1 | SUBSTITUTED 1,2,4-TRIAZOLO[4,3-A]PYRIDINE DERIVATIVE AND PREPARATION METHOD, HERBICIDAL COMPOSITION AND APPLICATION THEREOF | QINGDAO KINGAGROOT CHEMICAL COMPOUND CO., LTD. (CN) | 2023-03-09 | — | — | US | disclosed |
| US-10889571-B2 | Substituted benzoimidazoles and imidazo[4,5-c]pyridines for treating certain leukemias | Terns, Inc. (US) | 2021-01-12 | — | — | US | disclosed |
| US-20200087283-A1 | COMPOUNDS FOR TREATING CERTAIN LEUKEMIAS | Terns, Inc. (US) | 2020-03-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200087283-A1 | COMPOUNDS FOR TREATING CERTAIN LEUKEMIAS | ABL1, ABL2, BCR | CNR2 4682/4885CNR1 4740/4885TDP1 2132/4885 |
| US-20230075221-A1 | SUBSTITUTED 1,2,4-TRIAZOLO[4,3-A]PYRIDINE DERIVATIVE AND PREPARATION METHOD, HERBICIDAL COMPOSITION AND APPLICATION THEREOF | TH, CYP4X1, CYP4B1 | CNR2 1527/4885CNR1 1357/4885TDP1 1692/4885 |
| US-10889571-B2 | Substituted benzoimidazoles and imidazo[4,5-c]pyridines for treating certain leukemias | ABL1, ABL2, BCR | CNR2 4035/4885CNR1 4256/4885TDP1 2576/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.