Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM1 | P11229 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | GSK3B | P49841 | 2/20 | 0.33 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.32 |
| ▸ | CNR1 | P21554 | 4/20 | 0.32 |
| ▸ | CNR2 | P34972 | 2/20 | 0.32 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | CCR2 | P41597 | 1/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28577061 | 1.00 | CHRM1 (0.44) | CHRM1LMNAALDH1A1GSK3BDYRK1A | |
| SCHEMBL12989386 | 1.00 | CHRM1 (0.44) | CHRM1LMNAALDH1A1GSK3BDYRK1A | |
| SCHEMBL15431899 | 0.81 | CYP1A2 (0.48) | CHRM1GSK3BDYRK1ACYP1A2TDP1 | |
| SCHEMBL17625631 | 0.81 | CYP1A2 (0.48) | CHRM1GSK3BDYRK1ACYP1A2TDP1 | |
| SCHEMBL2901294 | 0.81 | CHRM1 (0.49) | CHRM1LMNAALDH1A1GSK3BDYRK1A | |
| SCHEMBL2379763 | 0.81 | CHRM1 (0.49) | CHRM1LMNAALDH1A1GSK3BDYRK1A | |
| SCHEMBL2908533 | 0.81 | CHRM1 (0.49) | CHRM1LMNAALDH1A1GSK3BDYRK1A | |
| SCHEMBL20434091 | 0.81 | CYP1A2 (0.48) | CHRM1GSK3BDYRK1ACYP1A2TDP1 | |
| SCHEMBL10565631 | 0.80 | CHRM1 (0.42) | CHRM1LMNAALDH1A1GSK3BDYRK1A | |
| SCHEMBL20279557 | 0.79 | TSHR (0.41) | LMNAALOX15TSHRHSD17B10HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112996784-B | Indole derivatives and their use in medicine | 北京越之康泰生物医药科技有限公司 | 2023-05-30 | — | — | CN | disclosed |
| CN-112996784-A | Indole derivatives and their use in medicine | 北京越之康泰生物医药科技有限公司 | 2021-06-18 | — | — | CN | disclosed |
| WO-2020057403-A1 | INDOLE DERIVATIVE AND MEDICAL APPLICATION THEREOF | 北京越之康泰生物医药科技有限公司 | 2020-03-26 | — | — | WO | disclosed |