⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21342140 | 0.83 | — | — | |
| SCHEMBL27535703 | 0.81 | KDM1A (0.30) | — | |
| SCHEMBL17359977 | 0.78 | TRPV1 (0.31) | — | |
| SCHEMBL26525948 | 0.75 | — | — | |
| SCHEMBL27281054 | 0.75 | — | — | |
| SCHEMBL27280242 | 0.75 | — | — | |
| SCHEMBL12827757 | 0.75 | — | — | |
| SCHEMBL11524261 | 0.73 | — | — | |
| SCHEMBL28621789 | 0.73 | — | — | |
| SCHEMBL13510920 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230072658-A1 | SMARCA DEGRADERS AND USES THEREOF | KYMERA THERAPEUTICS, INC. | 2023-03-09 | — | — | US | disclosed |
| WO-2020057403-A1 | INDOLE DERIVATIVE AND MEDICAL APPLICATION THEREOF | 北京越之康泰生物医药科技有限公司 | 2020-03-26 | — | — | WO | disclosed |