Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | IRAK1 | P51617 | 1/20 | 0.52 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.52 |
| ▸ | EGFR | P00533 | 5/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | ELANE | P08246 | 1/20 | 0.51 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.50 |
| ▸ | LCK | P06239 | 1/20 | 0.50 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.50 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.50 |
| ▸ | ATM | Q13315 | 1/20 | 0.48 |
| ▸ | KIT | P10721 | 1/20 | 0.48 |
| ▸ | CTSV | O60911 | 1/20 | 0.48 |
| ▸ | CTSL | P07711 | 1/20 | 0.48 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.47 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13271522 | 1.00 | KDM1A (0.53) | KDM1AMAPK1IRAK1IRAK4EGFR | |
| SCHEMBL10296328 | 0.90 | KDM1A (0.56) | KDM1AIRAK1IRAK4EGFRKDM4E | |
| SCHEMBL6592222 | 0.90 | KDM1A (0.56) | KDM1AIRAK1IRAK4EGFRKDM4E | |
| SCHEMBL21884823 | 0.89 | EGFR (0.50) | KDM1AMAPK1IRAK1IRAK4EGFR | |
| SCHEMBL14540552 | 0.85 | KDM1A (0.52) | KDM1AMAPK1IRAK1IRAK4EGFR | |
| SCHEMBL18676689 | 0.85 | KDM1A (0.52) | KDM1AMAPK1IRAK1IRAK4EGFR | |
| SCHEMBL30465578 | 0.85 | KDM1A (0.52) | KDM1AMAPK1IRAK1IRAK4EGFR | |
| SCHEMBL371731 | 0.85 | KDM1A (0.52) | KDM1AMAPK1IRAK1IRAK4EGFR | |
| SCHEMBL2062562 | 0.85 | KDM1A (0.52) | KDM1AMAPK1IRAK1IRAK4EGFR | |
| SCHEMBL30216650 | 0.85 | KDM1A (0.52) | KDM1AMAPK1IRAK1IRAK4EGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020057403-A1 | INDOLE DERIVATIVE AND MEDICAL APPLICATION THEREOF | 北京越之康泰生物医药科技有限公司 | 2020-03-26 | — | — | WO | disclosed |