Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR6 | P46095 | 12/20 | 0.38 |
| ▸ | TBK1 | Q9UHD2 | 1/20 | 0.38 |
| ▸ | PDE5A | O76074 | 1/20 | 0.36 |
| ▸ | PDE1A | P54750 | 1/20 | 0.36 |
| ▸ | PDE1B | Q01064 | 1/20 | 0.36 |
| ▸ | PDE1C | Q14123 | 1/20 | 0.36 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.36 |
| ▸ | AR | P10275 | 1/20 | 0.36 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.35 |
| ▸ | CDK9 | P50750 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21884436 | 0.87 | CCNT1 (0.41) | CCNT1CDK9 | |
| SCHEMBL21884411 | 0.73 | KDM4E (0.37) | SCN9A | |
| SCHEMBL21884660 | 0.71 | CCNT1 (0.40) | CCNT1CDK9 | |
| SCHEMBL23875079 | 0.71 | CCNT1 (0.42) | CCNT1CDK9 | |
| SCHEMBL21884630 | 0.69 | CCNT1 (0.40) | CCNT1CDK9 | |
| SCHEMBL24066316 | 0.69 | CCNT1 (0.40) | CCNT1CDK9 | |
| SCHEMBL24066294 | 0.69 | CCNT1 (0.41) | CCNT1CDK9 | |
| SCHEMBL21884605 | 0.69 | CCNT1 (0.40) | CCNT1CDK9 | |
| SCHEMBL21884638 | 0.69 | CCNT1 (0.41) | CCNT1CDK9 | |
| SCHEMBL21884371 | 0.68 | ABL1 (0.36) | CCNT1CDK9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020061473-A1 | SMALL MOLECULES TARGETING MUTANT MAMMALIAN PROTEINS | JNANA THERAPEUTICS, INC. (US) | 2020-03-26 | — | — | WO | disclosed |