Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCG2 | Q9UNQ0 | 5/20 | 0.41 |
| ▸ | MAOB | P27338 | 6/20 | 0.40 |
| ▸ | MAOA | P21397 | 2/20 | 0.39 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.39 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.38 |
| ▸ | BCHE | P06276 | 1/20 | 0.37 |
| ▸ | CNR2 | P34972 | 1/20 | 0.37 |
| ▸ | CYP1B1 | Q16678 | 3/20 | 0.36 |
| ▸ | CYP1A1 | P04798 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21801244 | 0.86 | ABCG2 (0.42) | ABCG2MAOBMAOAABCB1ABCC1 | |
| SCHEMBL21886437 | 0.85 | ABCG2 (0.41) | ABCG2MAOBABCB1ABCC1BCHE | |
| SCHEMBL21801126 | 0.84 | MAOB (0.42) | ABCG2MAOBMAOAABCB1ABCC1 | |
| SCHEMBL21886767 | 0.83 | CSNK2A2 (0.41) | ABCG2MAOBMAOACYP1B1CYP1A1 | |
| SCHEMBL21865634 | 0.81 | ABCB1 (0.43) | ABCG2MAOBABCB1ABCC1BCHE | |
| SCHEMBL21886755 | 0.81 | FFAR4 (0.32) | — | |
| SCHEMBL26680095 | 0.78 | MAOB (0.41) | ABCG2MAOBMAOAABCB1ABCC1 | |
| SCHEMBL21801127 | 0.76 | ABCB1 (0.38) | ABCG2MAOBMAOAABCB1ABCC1 | |
| SCHEMBL21801081 | 0.74 | CYSLTR1 (0.45) | MAOBMAOAABCB1BCHECNR2 | |
| SCHEMBL21801191 | 0.74 | CYSLTR1 (0.45) | MAOBMAOAABCB1BCHECNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020052774-A1 | FLAVONE DERIVATIVES FOR THE TREATMENT AND PROPHYLAXIS OF HEPATITIS B VIRUS DISEASE | F. HOFFMANN-LA ROCHE AG (CH) | 2020-03-19 | — | — | WO | disclosed |