Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 10/20 | 0.85 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.52 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.52 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.52 |
| ▸ | FPR2 | P25090 | 1/20 | 0.50 |
| ▸ | PROKR1 | Q8TCW9 | 1/20 | 0.50 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.50 |
| ▸ | ACACB | O00763 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL229024 | 0.92 | HRH3 (1.00) | HRH3PDE3BPDE3APDE10AFPR2 | |
| SCHEMBL20205990 | 0.88 | HRH3 (0.71) | HRH3FPR2PROKR1GPR119 | |
| SCHEMBL4236739 | 0.82 | HRH3 (0.84) | HRH3GPR119 | |
| SCHEMBL14578240 | 0.81 | HRH3 (0.56) | HRH3ACACB | |
| SCHEMBL4237843 | 0.81 | HRH3 (0.72) | HRH3 | |
| SCHEMBL24596869 | 0.80 | HRH3 (0.54) | HRH3ACACB | |
| SCHEMBL10267759 | 0.80 | HTR2C (0.59) | HRH3FPR2PROKR1ACACB | |
| SCHEMBL24596865 | 0.80 | HRH3 (0.54) | HRH3ACACB | |
| SCHEMBL15830259 | 0.80 | HTR2C (0.59) | HRH3FPR2PROKR1ACACB | |
| SCHEMBL189416 | 0.80 | HRH3 (0.54) | HRH3ACACB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020070610-A1 | NOVEL OXADIAZOLES | PI INDUSTRIES LTD. (IN) | 2020-04-09 | — | — | WO | disclosed |