Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21983391 | 1.00 | CYP1A2 (0.48) | CYP1A2ADRA2A | |
| SCHEMBL22485709 | 0.94 | CYP1A2 (0.41) | CYP1A2 | |
| SCHEMBL22820570 | 0.94 | CYP1A2 (0.41) | CYP1A2 | |
| SCHEMBL12089498 | 0.83 | CYP1A2 (0.52) | CYP1A2ADRA2A | |
| SCHEMBL12985779 | 0.83 | CYP1A2 (0.52) | CYP1A2ADRA2A | |
| SCHEMBL12090069 | 0.83 | CYP1A2 (0.52) | CYP1A2ADRA2A | |
| SCHEMBL26921123 | 0.80 | CYP1A2 (0.48) | CYP1A2ADRA2A | |
| SCHEMBL7269417 | 0.80 | CYP1A2 (0.48) | CYP1A2ADRA2A | |
| SCHEMBL24837418 | 0.78 | CYP1A2 (0.52) | CYP1A2ADRA2A | |
| SCHEMBL21944473 | 0.78 | CYP1A2 (0.47) | CYP1A2ADRA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10590108-B2 | Benzimidazoles for use in the treatment of cancer and inflammatory diseases | CAPELLA THERAPEUTICS, INC. (US) | 2020-03-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10590108-B2 | Benzimidazoles for use in the treatment of cancer and inflammatory diseases | CHKB, CHKA, CHUK | CYP1A2 418/4885ADRA2A 3748/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.