Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.63 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.63 |
| ▸ | MAPT | P10636 | 2/20 | 0.63 |
| ▸ | MEN1 | O00255 | 1/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.63 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.61 |
| ▸ | STS | P08842 | 2/20 | 0.60 |
| ▸ | CNR1 | P21554 | 1/20 | 0.58 |
| ▸ | HPGD | P15428 | 3/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.55 |
| ▸ | NPC1 | O15118 | 1/20 | 0.55 |
| ▸ | GMNN | O75496 | 1/20 | 0.55 |
| ▸ | USP2 | O75604 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | TP53 | P04637 | 1/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.55 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.55 |
| ▸ | IDE | P14735 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20543214 | 1.00 | HSD17B10 (0.63) | HSD17B10TRPV1MAPTMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL20543011 | 0.99 | HSD17B10 (0.61) | HSD17B10TRPV1MAPTMEN1KMT2A | |
| SCHEMBL30515391 | 0.88 | HPGD (0.67) | HSD17B10EPHX2HPGDNPC1RAB9A | |
| SCHEMBL14102656 | 0.86 | EPHX2 (0.65) | TRPV1MAPTMEN1KMT2AEPHX2 | |
| SCHEMBL1456740 | 0.85 | EPHX2 (0.80) | HSD17B10TRPV1MAPTMEN1KMT2A | |
| SCHEMBL18328442 | 0.85 | EPHX2 (0.72) | TRPV1MAPTMEN1KMT2AEPHX2 | |
| SCHEMBL14102773 | 0.85 | EPHX2 (0.72) | TRPV1MAPTMEN1KMT2AEPHX2 | |
| SCHEMBL19043177 | 0.85 | EPHX2 (0.80) | HSD17B10TRPV1MAPTMEN1KMT2A | |
| SCHEMBL4183114 | 0.85 | EPHX2 (0.80) | HSD17B10TRPV1MAPTMEN1KMT2A | |
| SCHEMBL30445464 | 0.85 | EPHX2 (0.80) | HSD17B10TRPV1MAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2342180-A2 | ORGANIC COMPOUNDS SUITABLE FOR MODULATING FRAGRANCE COMPOSITIONS | Givaudan SA (CH) | 2011-07-13 | — | — | EP | disclosed |
| WO-2010037244-A2 | ORGANIC COMPOUNDS | GIVAUDAN SA (CH) | 2010-04-08 | — | — | WO | disclosed |