Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 14/20 | 0.76 |
| ▸ | NAALAD2 | Q9Y3Q0 | 5/20 | 0.72 |
| ▸ | RIMKLA | Q8IXN7 | 1/20 | 0.72 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18647145 | 0.91 | FOLH1 (0.81) | FOLH1NAALAD2RIMKLA | |
| SCHEMBL13429995 | 0.91 | FOLH1 (0.81) | FOLH1NAALAD2RIMKLA | |
| SCHEMBL16731665 | 0.91 | FOLH1 (0.81) | FOLH1NAALAD2RIMKLA | |
| SCHEMBL18329612 | 0.91 | FOLH1 (0.81) | FOLH1NAALAD2RIMKLA | |
| SCHEMBL18647212 | 0.91 | FOLH1 (0.81) | FOLH1NAALAD2RIMKLA | |
| SCHEMBL18608749 | 0.91 | FOLH1 (0.81) | FOLH1NAALAD2RIMKLA | |
| SCHEMBL18647405 | 0.91 | FOLH1 (0.81) | FOLH1NAALAD2RIMKLA | |
| SCHEMBL20698817 | 0.87 | FOLH1 (0.65) | FOLH1NAALAD2RIMKLA | |
| SCHEMBL21321539 | 0.86 | FOLH1 (0.67) | FOLH1NAALAD2RIMKLA | |
| SCHEMBL16731658 | 0.86 | FOLH1 (0.64) | FOLH1NAALAD2RIMKLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10624970-B2 | PSMA binding ligand-linker conjugates and methods for using | PURDUE RESEARCH FOUNDATION (US) | 2020-04-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10624970-B2 | PSMA binding ligand-linker conjugates and methods for using | FOLH1, KLK3, PSMA1 | FOLH1 1/4885NAALAD2 49/4885RIMKLA 513/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.