Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMPD3 | Q9NY59 | 2/20 | 0.33 |
| ▸ | AXL | P30530 | 1/20 | 0.33 |
| ▸ | CDK2 | P24941 | 1/20 | 0.31 |
| ▸ | JAK1 | P23458 | 1/20 | 0.30 |
| ▸ | PIK3C3 | Q8NEB9 | 1/20 | 0.30 |
| ▸ | KCNQ3 | O43525 | 1/20 | 0.30 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21849000 | 0.79 | SMPD3 (0.33) | SMPD3AXLCDK2 | |
| SCHEMBL803428 | 0.75 | SMPD3 (0.55) | SMPD3AXLCDK2JAK1PIK3C3 | |
| SCHEMBL21849007 | 0.70 | SSTR4 (0.33) | — | |
| SCHEMBL3711979 | 0.66 | SMPD3 (0.43) | SMPD3AXLKCNQ3KCNQ2 | |
| SCHEMBL26032356 | 0.65 | PDE10A (0.31) | — | |
| SCHEMBL14752169 | 0.65 | PIK3CG (0.42) | SMPD3AXLCDK2KCNQ3KCNQ2 | |
| SCHEMBL15306539 | 0.65 | PIK3CG (0.54) | SMPD3AXLCDK2KCNQ3KCNQ2 | |
| SCHEMBL19863991 | 0.64 | SMPD3 (0.49) | SMPD3AXLCDK2JAK1PIK3C3 | |
| SCHEMBL15306541 | 0.63 | PDE2A (0.39) | — | |
| SCHEMBL29297307 | 0.63 | FLT1 (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020065613-A1 | MONOACYLGLYCEROL LIPASE MODULATORS | JANSSEN PHARMACEUTICA NV (BE) | 2020-04-02 | — | — | WO | disclosed |