Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 7/20 | 0.81 |
| ▸ | HTR2A | P28223 | 6/20 | 0.81 |
| ▸ | HTR2B | P41595 | 6/20 | 0.81 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | CNR1 | P21554 | 1/20 | 0.38 |
| ▸ | CNR2 | P34972 | 1/20 | 0.38 |
| ▸ | PRCP | P42785 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1475300 | 0.90 | HTR2A (1.00) | HTR2CHTR2AHTR2BALDH1A1MAPK10 | |
| SCHEMBL2075189 | 0.88 | HTR2A (0.81) | HTR2CHTR2AHTR2BALDH1A1MAPK10 | |
| SCHEMBL1476190 | 0.81 | HTR2A (0.82) | HTR2CHTR2AHTR2BALDH1A1 | |
| SCHEMBL1475799 | 0.81 | HTR2A (0.82) | HTR2CHTR2AHTR2BPTGS2PTGS1 | |
| SCHEMBL1476015 | 0.81 | HTR2A (0.82) | HTR2CHTR2AHTR2B | |
| SCHEMBL1475759 | 0.81 | HTR2A (0.82) | HTR2CHTR2AHTR2BPTGS2PTGS1 | |
| SCHEMBL21818664 | 0.81 | HTR2C (0.56) | HTR2CHTR2AHTR2B | |
| SCHEMBL21819191 | 0.78 | HTR2C (0.82) | HTR2CHTR2AHTR2B | |
| SCHEMBL1476430 | 0.78 | HTR2A (0.76) | HTR2CHTR2AHTR2BALDH1A1PTGS2 | |
| SCHEMBL1476390 | 0.78 | HTR2C (0.76) | HTR2CHTR2AHTR2BCYP1A2CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020065613-A1 | MONOACYLGLYCEROL LIPASE MODULATORS | JANSSEN PHARMACEUTICA NV (BE) | 2020-04-02 | — | — | WO | disclosed |