Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 8/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.48 |
| ▸ | TP53 | P04637 | 4/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.48 |
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
| ▸ | CCR1 | P32246 | 2/20 | 0.48 |
| ▸ | CCR5 | P51681 | 2/20 | 0.48 |
| ▸ | CCR8 | P51685 | 2/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | METAP1 | P53582 | 1/20 | 0.48 |
| ▸ | BLM | P54132 | 1/20 | 0.48 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.48 |
| ▸ | DOHH | Q9BU89 | 1/20 | 0.48 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 7/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7183205 | 0.81 | KDM4E (0.38) | NPC1SMN1; SMN2TP53KDM4ELMNA | |
| Hydrochloric Acid SCHEMBL7171654 | 0.81 | KDM4E (0.38) | NPC1SMN1; SMN2TP53KDM4ELMNA | |
| Hydrochloric Acid SCHEMBL7171297 | 0.81 | KDM4E (0.38) | NPC1SMN1; SMN2TP53KDM4ELMNA | |
| Hydrochloric Acid SCHEMBL7181352 | 0.81 | TP53 (0.38) | NPC1SMN1; SMN2TP53KDM4ELMNA | |
| Hydrochloric Acid SCHEMBL7175992 | 0.81 | KDM4E (0.38) | NPC1SMN1; SMN2TP53KDM4ELMNA | |
| Hydrochloric Acid SCHEMBL7177150 | 0.81 | KDM4E (0.38) | NPC1SMN1; SMN2TP53KDM4ELMNA | |
| Hydrochloric Acid SCHEMBL7179144 | 0.81 | KDM4E (0.38) | NPC1SMN1; SMN2TP53KDM4ELMNA | |
| SCHEMBL21893886 | 0.79 | NPC1 (0.43) | NPC1SMN1; SMN2TP53TSHRKDM4E | |
| SCHEMBL19244945 | 0.79 | NPC1 (0.43) | NPC1SMN1; SMN2TP53TSHRKDM4E | |
| SCHEMBL21818931 | 0.76 | NPC1 (0.47) | NPC1SMN1; SMN2TP53TSHRKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113200962-B | Phenylimidazole compounds | 株式会社大塚制药工场 | 2024-10-18 | — | — | CN | disclosed |
| WO-2020065613-A1 | MONOACYLGLYCEROL LIPASE MODULATORS | JANSSEN PHARMACEUTICA NV (BE) | 2020-04-02 | — | — | WO | disclosed |