Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.38 |
| ▸ | HTT | P42858 | 3/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | PPARG | P37231 | 1/20 | 0.34 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.34 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.34 |
| ▸ | TXNRD1 | Q16881 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18885140 | 0.80 | SMN1; SMN2 (0.40) | TSHRALDH1A1HTTPOLBLMNA | |
| SCHEMBL21142427 | 0.77 | MAPT (0.43) | ALDH1A1HTTPOLBSMN1; SMN2MAPT | |
| SCHEMBL24936781 | 0.73 | HSD17B10 (0.46) | TSHRALDH1A1HTTPOLBSMN1; SMN2 | |
| SCHEMBL982872 | 0.68 | TSHR (0.49) | TSHRALDH1A1HTTPOLBLMNA | |
| SCHEMBL986005 | 0.68 | TSHR (0.49) | TSHRALDH1A1HTTPOLBLMNA | |
| SCHEMBL980381 | 0.68 | TSHR (0.49) | TSHRALDH1A1HTTPOLBLMNA | |
| SCHEMBL985318 | 0.68 | TSHR (0.49) | TSHRALDH1A1HTTPOLBLMNA | |
| SCHEMBL983685 | 0.68 | TSHR (0.49) | TSHRALDH1A1HTTPOLBLMNA | |
| SCHEMBL984099 | 0.68 | TSHR (0.49) | TSHRALDH1A1HTTPOLBLMNA | |
| SCHEMBL19478610 | 0.67 | MAPT (0.46) | TSHRALDH1A1HTTPOLBLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11773052-B2 | Enamine compound and use thereof | JAPAN SCIENCE AND TECHNOLOGY AGENCY (JP) | 2023-10-03 | — | — | US | disclosed |
| US-20200087245-A1 | ENAMINE COMPOUND AND USE THEREOF | JAPAN SCIENCE AND TECHNOLOGY AGENCY (JP) | 2020-03-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200087245-A1 | ENAMINE COMPOUND AND USE THEREOF | ENY2, AHR, PAH | TSHR 1119/4885ALDH1A1 974/4885HTT 2086/4885 |
| US-11773052-B2 | Enamine compound and use thereof | ENY2, AHR, PAH | TSHR 1119/4885ALDH1A1 974/4885HTT 2086/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.