Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AURKA | O14965 | 2/20 | 0.42 |
| ▸ | PDE3B | Q13370 | 8/20 | 0.39 |
| ▸ | PDE3A | Q14432 | 8/20 | 0.39 |
| ▸ | DAO | P14920 | 2/20 | 0.33 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.33 |
| ▸ | SYK | P43405 | 1/20 | 0.32 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8664696 | 0.73 | LIMK1 (0.39) | AURKAPDE3BPDE3AAURKB | |
| SCHEMBL21895411 | 0.70 | PDE3B (0.37) | AURKAPDE3BPDE3ASYK | |
| SCHEMBL341252 | 0.67 | PDE3B (0.49) | AURKAPDE3BPDE3ADAOSYK | |
| SCHEMBL339945 | 0.66 | PDE3B (0.40) | AURKAPDE3BPDE3ADAO | |
| SCHEMBL21895410 | 0.65 | AURKA (0.45) | AURKADAOPTPN11 | |
| SCHEMBL3816282 | 0.65 | PDPK1 (0.43) | AURKAPDE3BPDE3ASYK | |
| SCHEMBL9039612 | 0.63 | AURKA (0.58) | AURKAPDE3BPDE3ADAOAURKB | |
| SCHEMBL29585324 | 0.62 | MEN1 (0.39) | — | |
| SCHEMBL338384 | 0.62 | RPS6KA3 (0.52) | — | |
| SCHEMBL23679798 | 0.61 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3854799-B1 | CYCLIC DINUCLEOTIDE ANALOGUE, PHARMACEUTICAL COMPOSITION THEREOF, AND APPLICATION | SHANGHAI DE NOVO PHARMATECH CO LTD (CN) | 2024-07-17 | — | — | EP | disclosed |
| EP-3854799-A1 | CYCLIC DINUCLEOTIDE ANALOGUE, PHARMACEUTICAL COMPOSITION THEREOF, AND APPLICATION | Shanghai de Novo Pharmatech Co., Ltd. (CN) | 2021-07-28 | — | — | EP | disclosed |
| WO-2020057546-A1 | CYCLIC DINUCLEOTIDE ANALOGUE, PHARMACEUTICAL COMPOSITION THEREOF, AND APPLICATION | 上海迪诺医药科技有限公司 | 2020-03-26 | — | — | WO | disclosed |