Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | KIT | P10721 | 11/20 | 0.36 |
| ▸ | BRAF | P15056 | 11/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.32 |
| ▸ | WNT3A | P56704 | 1/20 | 0.32 |
| ▸ | AURKA | O14965 | 1/20 | 0.32 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.32 |
| ▸ | CSNK1E | P49674 | 1/20 | 0.32 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21899383 | 0.95 | HTT (0.34) | HTTNPSR1KITBRAFCYP1A2 | |
| SCHEMBL21899365 | 0.95 | CYP1A2 (0.35) | HTTNPSR1KITBRAFCYP1A2 | |
| SCHEMBL23082529 | 0.93 | CSNK1E (0.34) | HTTNPSR1KITBRAFCYP1A2 | |
| SCHEMBL21965340 | 0.92 | HTT (0.42) | HTTNPSR1KITBRAFCYP1A2 | |
| SCHEMBL28523238 | 0.91 | CSNK1E (0.33) | HTTNPSR1KITBRAFCYP1A2 | |
| SCHEMBL21965335 | 0.90 | HTT (0.36) | HTTNPSR1KITBRAFCYP1A2 | |
| SCHEMBL1767229 | 0.85 | KDM4E (0.36) | SMN1; SMN2RAB9APOLBMAPT | |
| SCHEMBL23082573 | 0.85 | NPSR1 (0.36) | HTTNPSR1KITBRAFCYP1A2 | |
| SCHEMBL28992866 | 0.85 | CTNNB1 (0.32) | CYP1A2CYP2C9CYP2C19SMN1; SMN2RAB9A | |
| SCHEMBL1766774 | 0.84 | KCNJ11 (0.36) | BRAFSMN1; SMN2RAB9APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115872901-A | Imine compound and application thereof | 沈阳中化农药化工研发有限公司 | 2023-03-31 | — | — | CN | disclosed |
| EP-4026831-A1 | PIPERIC ACID DERIVATIVE AND APPLICATION THEREOF | Shenyang Sinochem Agrochemicals R&D Co., Ltd. (CN) | 2022-07-13 | — | — | EP | disclosed |
| US-20220202011-A1 | PIPERIC ACID DERIVATIVE AND APPLICATION THEREOF | JIANGSU YANGNONG CHEMICAL CO., LTD (CN) | 2022-06-30 | — | — | US | disclosed |
| CN-109206397-B | Piperamic acid derivative and preparation and application thereof | 沈阳中化农药化工研发有限公司 | 2022-06-07 | — | — | CN | disclosed |
| EP-3647305-B1 | PIPERIC ACID DERIVATIVE AND PREPARATION AND APPLICATION THEREOF | SHENYANG SINOCHEM AGROCHEMICALS R & D CO LTD (CN) | 2022-02-23 | — | — | EP | disclosed |
| EP-3647305-B1 | PIPERIC ACID DERIVATIVE AND PREPARATION AND APPLICATION THEREOF | SHENYANG SINOCHEM AGROCHEMICALS R & D CO LTD (CN) | 2022-02-23 | — | — | EP | disclosed |
| WO-2021043115-A1 | PIPERIC ACID DERIVATIVE AND APPLICATION THEREOF | 沈阳中化农药化工研发有限公司 | 2021-03-11 | — | — | WO | disclosed |
| US-20200181107-A1 | PIPERONYLIC ACID DERIVATIVE AND PREPARATION AND APPLICATION THEREOF | SHENYANG SINOCHEM AGROCHEMICALS R&D CO., LTD. (CN) | 2020-06-11 | — | — | US | disclosed |
| EP-3647305-A1 | PIPERIC ACID DERIVATIVE AND PREPARATION AND APPLICATION THEREOF | Shenyang Sinochem Agrochemicals R & D Co., Ltd. (CN) | 2020-05-06 | — | — | EP | disclosed |
| EP-3647305-A1 | PIPERIC ACID DERIVATIVE AND PREPARATION AND APPLICATION THEREOF | Shenyang Sinochem Agrochemicals R & D Co., Ltd. (CN) | 2020-05-06 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220202011-A1 | PIPERIC ACID DERIVATIVE AND APPLICATION THEREOF | ALDH7A1, CAT, PIR | HTT 4187/4885NPSR1 2045/4885KIT 1994/4885 |
| US-20200181107-A1 | PIPERONYLIC ACID DERIVATIVE AND PREPARATION AND APPLICATION THEREOF | CYP51A1, DDT, PIR | HTT 3712/4885NPSR1 2578/4885KIT 2890/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.