Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25630384 | 0.68 | — | — | |
| SCHEMBL22383715 | 0.67 | HSD17B10 (0.30) | — | |
| SCHEMBL21604059 | 0.66 | GAA (0.38) | MEN1KMT2A | |
| SCHEMBL13868576 | 0.64 | CA12 (0.34) | MEN1TSHRKMT2A | |
| SCHEMBL17319432 | 0.64 | — | — | |
| SCHEMBL10041976 | 0.63 | MEN1 (0.39) | MEN1KMT2A | |
| SCHEMBL20049944 | 0.62 | — | — | |
| SCHEMBL18938460 | 0.61 | — | — | |
| SCHEMBL20725738 | 0.60 | — | — | |
| SCHEMBL19435716 | 0.59 | KDM4E (0.39) | MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020081636-A1 | INDOLE AHR INHIBITORS AND USES THEREOF | Ikena Oncology, Inc. (US) | 2020-04-23 | — | — | WO | disclosed |