Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.80 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.80 |
| ▸ | HPGD | P15428 | 6/20 | 0.80 |
| ▸ | DRD2 | P14416 | 6/20 | 0.80 |
| ▸ | MAPT | P10636 | 5/20 | 0.80 |
| ▸ | MAPK1 | P28482 | 5/20 | 0.80 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.80 |
| ▸ | HTR1A | P08908 | 5/20 | 0.80 |
| ▸ | TP53 | P04637 | 4/20 | 0.80 |
| ▸ | PKM | P14618 | 4/20 | 0.80 |
| ▸ | LMNA | P02545 | 4/20 | 0.80 |
| ▸ | CYP2C9 | P11712 | 4/20 | 0.80 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.80 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.80 |
| ▸ | GAA | P10253 | 3/20 | 0.80 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.80 |
| ▸ | MEN1 | O00255 | 2/20 | 0.80 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.80 |
| ▸ | MDM2 | Q00987 | 2/20 | 0.80 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.80 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| (S)Apomorphine SCHEMBL30554804 | 0.89 | KDM4E (1.00) | KDM4EALDH1A1HPGDDRD2MAPT | |
| Apomorphine SCHEMBL29599870 | 0.89 | KDM4E (1.00) | KDM4EALDH1A1HPGDDRD2MAPT | |
| Apomorphine SCHEMBL1923763 | 0.89 | KDM4E (1.00) | KDM4EALDH1A1HPGDDRD2MAPT | |
| Apomorphine SCHEMBL8541 | 0.89 | KDM4E (1.00) | KDM4EALDH1A1HPGDDRD2MAPT | |
| Apomorphine SCHEMBL29414090 | 0.89 | KDM4E (1.00) | KDM4EALDH1A1HPGDDRD2MAPT | |
| (S)Apomorphine SCHEMBL6922802 | 0.89 | KDM4E (1.00) | KDM4EALDH1A1HPGDDRD2MAPT | |
| Apomorphine SCHEMBL5605456 | 0.89 | KDM4E (1.00) | KDM4EALDH1A1HPGDDRD2MAPT | |
| Apomorphine SCHEMBL29358024 | 0.89 | KDM4E (1.00) | KDM4EALDH1A1HPGDDRD2MAPT | |
| Apomorphine SCHEMBL5678746 | 0.88 | KDM4E (0.97) | KDM4EALDH1A1HPGDDRD2MAPT | |
| (S)Apomorphine SCHEMBL19469972 | 0.88 | KDM4E (1.00) | KDM4EALDH1A1HPGDDRD2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020081973-A1 | TREATMENT OF NEUROLOGICAL DISEASES | ACLIPSE ONE INC. (US) | 2020-04-23 | — | — | WO | disclosed |