Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21902106 | 0.95 | GRIN2B (0.80) | GRIN2BRXRB | |
| SCHEMBL21902081 | 0.90 | GRIN2B (1.00) | GRIN2BRXRB | |
| SCHEMBL24892978 | 0.88 | RXRB (1.00) | GRIN2BRXRB | |
| SCHEMBL21906399 | 0.88 | RXRB (1.00) | GRIN2BRXRB | |
| SCHEMBL21902102 | 0.87 | GRIN2B (0.80) | GRIN2BRXRB | |
| SCHEMBL21941011 | 0.87 | GRIN2B (0.80) | GRIN2BRXRB | |
| SCHEMBL21903004 | 0.84 | GRIN2B (1.00) | GRIN2BRXRB | |
| SCHEMBL24713396 | 0.84 | GRIN2B (1.00) | GRIN2BRXRB | |
| SCHEMBL21902117 | 0.83 | GRIN2B (0.80) | GRIN2BRXRB | |
| SCHEMBL21902115 | 0.83 | GRIN2B (0.80) | GRIN2BRXRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11155539-B2 | 4-pyridinylmethyl-morpholine derivatives and the use thereof as medicament | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2021-10-26 | — | — | US | disclosed |
| US-20200123141-A1 | 4-Pyridinylmethyl-Morpholine Derivatives and the use thereof as Medicament | BOEHRINGER INGELHEIM PHARMA GMBH & CO. KG (DE) | 2020-04-23 | — | — | US | disclosed |
| WO-2020079042-A1 | 4-PYRIDINYLMETHYL-MORPHOLINE DERIVATIVES AND THE USE THEREOF AS MEDICAMENT | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2020-04-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11155539-B2 | 4-pyridinylmethyl-morpholine derivatives and the use thereof as medicament | GRIN2A, GRIN2C, GRIN3A | GRIN2B 5/4885RXRB 519/4885 |
| US-20200123141-A1 | 4-Pyridinylmethyl-Morpholine Derivatives and the use thereof as Medicament | GRIN2A, GRIN2C, GRIN3A | GRIN2B 5/4885RXRB 519/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.