Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.51 |
| ▸ | RECQL | P46063 | 1/20 | 0.51 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.50 |
| ▸ | PNMT | P11086 | 2/20 | 0.49 |
| ▸ | PYCR1 | P32322 | 1/20 | 0.48 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.47 |
| ▸ | RORC | P51449 | 1/20 | 0.46 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.45 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | BCHE | P06276 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.43 |
| ▸ | HTR1A | P08908 | 1/20 | 0.43 |
| ▸ | HTR2C | P28335 | 1/20 | 0.43 |
| ▸ | HTR2B | P41595 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21902245 | 0.91 | TSHR (0.49) | TSHRRECQLTAAR1PNMTPYCR1 | |
| SCHEMBL31500392 | 0.89 | TSHR (0.53) | TSHRRECQLTAAR1PNMTPYCR1 | |
| SCHEMBL11466186 | 0.89 | TSHR (0.53) | TSHRRECQLTAAR1PNMTPYCR1 | |
| SCHEMBL21902239 | 0.84 | TSHR (0.51) | TSHRRECQLTAAR1PNMTPYCR1 | |
| SCHEMBL26655849 | 0.84 | TAAR1 (0.46) | TSHRRECQLTAAR1PNMTPYCR1 | |
| SCHEMBL26655848 | 0.84 | TSHR (0.48) | TSHRRECQLTAAR1PNMTPYCR1 | |
| SCHEMBL11465237 | 0.80 | HRH3 (0.58) | TAAR1PYCR1AOC3RORCCYP1A2 | |
| SCHEMBL16144721 | 0.80 | CARM1 (0.58) | TSHRAOC3RORCCARM1HSD17B10 | |
| SCHEMBL26658419 | 0.79 | TAAR1 (0.47) | TSHRRECQLTAAR1PNMTPYCR1 | |
| SCHEMBL21902241 | 0.79 | CARM1 (0.62) | TSHRRECQLTAAR1PNMTPYCR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210347846-A1 | NOVEL MEANS TO MODULATE NMDA RECEPTOR-MEDIATED TOXICITY | FUNDAMENTAL PHARMA GMBH (DE) | 2021-11-11 | — | — | US | disclosed |
| WO-2020079244-A1 | NOVEL MEANS TO MODULATE NMDA RECEPTOR-MEDIATED TOXICITY | FUNDAMENTAL PHARMA GMBH (DE) | 2020-04-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210347846-A1 | NOVEL MEANS TO MODULATE NMDA RECEPTOR-MEDIATED TOXICITY | TRPM4, GRIK4, GRM4 | TSHR 1493/4885RECQL 3884/4885TAAR1 1186/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.