Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.60 |
| ▸ | LGALS3 | P17931 | 2/20 | 0.48 |
| ▸ | LGALS8 | O00214 | 1/20 | 0.48 |
| ▸ | LGALS4 | P56470 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | B4GALT1 | P15291 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 2/20 | 0.39 |
| ▸ | CA2 | P00918 | 2/20 | 0.39 |
| ▸ | CA9 | Q16790 | 2/20 | 0.39 |
| ▸ | CD69 | Q07108 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | ADAMTS5 | Q9UNA0 | 2/20 | 0.37 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19871871 | 0.92 | MAPK1 (0.58) | MAPK1LGALS3LGALS8LGALS4ALDH1A1 | |
| SCHEMBL18929646 | 0.92 | MAPK1 (0.62) | MAPK1LGALS3LGALS8LGALS4ALDH1A1 | |
| SCHEMBL20016515 | 0.92 | MAPK1 (0.62) | MAPK1LGALS3LGALS8LGALS4ALDH1A1 | |
| SCHEMBL18627852 | 0.91 | MAPK1 (0.60) | MAPK1LGALS3LGALS8LGALS4ALDH1A1 | |
| SCHEMBL13813121 | 0.91 | MAPK1 (0.60) | MAPK1LGALS3LGALS8LGALS4ALDH1A1 | |
| SCHEMBL24646161 | 0.90 | MAPK1 (0.55) | MAPK1LGALS3LGALS8LGALS4ALDH1A1 | |
| SCHEMBL19062174 | 0.90 | MAPK1 (0.55) | MAPK1LGALS3LGALS8LGALS4ALDH1A1 | |
| SCHEMBL18627853 | 0.89 | MAPK1 (0.54) | MAPK1LGALS3LGALS8LGALS4ALDH1A1 | |
| SCHEMBL20053489 | 0.89 | MAPK1 (0.54) | MAPK1LGALS3LGALS8LGALS4ALDH1A1 | |
| SCHEMBL22226885 | 0.89 | MAPK1 (0.54) | MAPK1LGALS3LGALS8LGALS4ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10793862-B2 | Compositions and methods for modulating growth hormone receptor expression | IONIS PHARMACEUTICALS, INC. (US) | 2020-10-06 | — | — | US | disclosed |
| US-20200123551-A1 | COMPOSITIONS AND METHODS FOR MODULATING GROWTH HORMONE RECEPTOR EXPRESSION | IONIS PHARMACEUTICALS, INC. (US) | 2020-04-23 | — | — | US | disclosed |