⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20128761 | 0.87 | — | — | |
| SCHEMBL20128800 | 0.84 | — | — | |
| SCHEMBL20128863 | 0.83 | — | — | |
| SCHEMBL20128778 | 0.83 | — | — | |
| SCHEMBL20128781 | 0.83 | — | — | |
| SCHEMBL20128784 | 0.82 | GRIN1 (0.30) | — | |
| SCHEMBL21664605 | 0.79 | — | — | |
| SCHEMBL20128787 | 0.79 | — | — | |
| SCHEMBL20325672 | 0.79 | — | — | |
| SCHEMBL20128763 | 0.77 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10604506-B2 | Modulators of estrogen receptor proteolysis and associated methods of use | ARVINAS OPERATIONS, INC. (US) | 2020-03-31 | — | — | US | disclosed |