Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21187534 | 0.83 | RET (0.42) | RET | |
| SCHEMBL21191323 | 0.79 | RET (0.45) | RET | |
| SCHEMBL21187545 | 0.76 | RET (0.45) | RET | |
| SCHEMBL24632318 | 0.76 | — | — | |
| SCHEMBL24490662 | 0.75 | — | — | |
| SCHEMBL24192087 | 0.75 | RET (0.31) | RET | |
| SCHEMBL21191286 | 0.73 | RET (0.36) | RET | |
| SCHEMBL21907115 | 0.73 | RET (0.33) | RORCRET | |
| SCHEMBL21187547 | 0.72 | RET (0.38) | RET | |
| SCHEMBL24632337 | 0.71 | RET (0.41) | RET |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020055672-A1 | FUSED HETEROCYCLIC COMPOUNDS AS RET KINASE INHIBITORS | ARRAY BIOPHARMA INC. (US) | 2020-03-19 | — | — | WO | disclosed |