Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCD | O00767 | 17/20 | 0.72 |
| ▸ | NPC1 | O15118 | 4/20 | 0.72 |
| ▸ | RAB9A | P51151 | 4/20 | 0.72 |
| ▸ | MEN1 | O00255 | 3/20 | 0.72 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.72 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.61 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.61 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.57 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.57 |
| ▸ | HTT | P42858 | 1/20 | 0.57 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.57 |
| ▸ | HPGD | P15428 | 1/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21376822 | 0.94 | SCD (0.62) | SCDNPC1RAB9AMEN1KMT2A | |
| SCHEMBL13490124 | 0.85 | SCD (0.82) | SCDNPC1RAB9AMEN1KMT2A | |
| SCHEMBL31243 | 0.85 | SCD (1.00) | SCDNPC1RAB9AMEN1KMT2A | |
| SCHEMBL21910767 | 0.82 | SCD (0.58) | SCDNPC1RAB9AMEN1KMT2A | |
| SCHEMBL663943 | 0.82 | SCD (0.73) | SCDNPC1RAB9AMEN1KMT2A | |
| SCHEMBL2753553 | 0.81 | SCD (0.93) | SCDNPC1RAB9AMEN1KMT2A | |
| SCHEMBL21376926 | 0.81 | SCD (0.74) | SCDNPC1RAB9AMEN1KMT2A | |
| SCHEMBL2484653 | 0.80 | SCD (0.81) | SCDNPC1RAB9AMEN1KMT2A | |
| SCHEMBL16562121 | 0.80 | SCD (0.89) | SCDNPC1RAB9AMEN1KMT2A | |
| SCHEMBL16554145 | 0.79 | SCD (0.88) | SCDNPC1RAB9AMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3626240-A1 | PROCESS OF PREPARATION OF A N-ARYL BENZYL SULFONAMIDE SUBSTITUTED WITH AN AMIDO GROUP | StemSynergy Therapeutics, Inc. (US) | 2020-03-25 | — | — | EP | disclosed |